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Statistical methods

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The article was published on 1967-01-01 and is currently open access. It has received 22994 citations till now.

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Experimental Subendocardial Ischemia in Dogs with Normal Coronary Arteries

TL;DR: This study studied subendocardial ischemia without anatomic coronary artery obstruction in open-chest anesthetized dogs and measured pressures in aorta and left ventricle, phasic left coronary arterial blood flow by electromagnetic flowmeter and altered flow ratios were best predicted by relating them to the ratio of DPTI to TTI.
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“Proving the null hypothesis” in clinical trials

TL;DR: Test statistics, confidence intervals, and sample size calculations are discussed, and the required sample size may be larger for either null hypothesis formulation than for the other, depending on the specific assumptions made.
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Nosocomial pneumonia in patients receiving continuous mechanical ventilation. Prospective analysis of 52 episodes with use of a protected specimen brush and quantitative culture techniques.

TL;DR: To determine prognostic and descriptive factors of ventilator-associated (V-A) pneumonia, 567 patients who had been receiving mechanical ventilation for more than 3 days in a unit were prospectively studied.
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Managerial succession and firm performance

TL;DR: Turnover announcements are associated with significantly positive average abnormal stock returns, which are in turn significantly positively related to subsequent changes in accounting measures of performance as mentioned in this paper, suggesting that investors view turnover announcements as good news presaging performance improvements.
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An analysis of dose-effect relationship in the radiotherapy of malignant gliomas.

TL;DR: It was concluded that radiotherapy had a significant influence on the survival of patients with malignant glioma and that a clear-cut dose-effect relationship exists.