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Statistical methods
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The article was published on 1967-01-01 and is currently open access. It has received 22994 citations till now.read more
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Journal ArticleDOI
Prenatal Micronutrient Supplementation and Intellectual and Motor Function in Early School-aged Children in Nepal
Parul Christian,Laura E. Murray-Kolb,Subarna K. Khatry,Joanne Katz,Barbara A. Schaefer,Pamela M. Cole,Steven C. LeClerq,James M. Tielsch +7 more
TL;DR: Aspects of intellectual functioning including working memory, inhibitory control, and fine motor functioning among offspring were positively associated with prenatal iron/folic acid supplementation in an area where iron deficiency is prevalent.
Journal ArticleDOI
Double-blind randomised trial of intravenous tissue-type plasminogen activator versus placebo in acute myocardial infarction
M. Verstraete,Ronald W. Brower,Desire Collen,A.J. Dunning,Jacobus Lubsen,P.L. Michel,Joachim Schofer,Vanhaecke J,F. Van de Werf,Walter Bleifeld,Charbonnier B,D.P. de Bono,R.J. Lennane,Detlef G. Mathey,Ph. Raynaud,A Vahanian,G.A.vande Kley,R. Von Essen +17 more
TL;DR: In a double-blind randomised trial 129 patients with first myocardial infarction of less than 6 h duration were allocated to treatment with human recombinant tissue-type plasminogen activator (rt-PA) given intravenously over 90 min, or to placebo infusion.
Journal ArticleDOI
Autonomic Mechanisms in Hemodynamic Responses to Isometric Exercise
C. Edwin Martin,James A. Shaver,Donald F. Leon,Mark E. Thompson,Pesara S. Reddy,James J. Leonard +5 more
TL;DR: The role of the sympathetic nervous system was delineated in the heart rate and pressor responses to sustained handgrip and it was concluded that the increase in resistance was the result of sympathetically induced vasoconstriction.
Journal ArticleDOI
Prolongation of the Q-T Interval in Man During Sleep
Kevin F. Browne,Kevin F. Browne,Eric N. Prystowsky,Eric N. Prystowsky,James J. Heger,James J. Heger,Donald A. Chilson,Donald A. Chilson,Douglas P. Zipes,Douglas P. Zipes +9 more
TL;DR: Statistics indicate that the Q-T interval is longer during sleep than during the awake state at the same heart rate, which may reflect increased vagal tone or sympathetic withdrawal and changes in repolarization related to the diurnal variation of some ventricular arrhythmias.
Journal ArticleDOI
IL-2-based immunotherapy after autologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: a phase I/II trial
Linda J. Burns,Daniel J. Weisdorf,Todd E. DeFor,David H. Vesole,Tanya Repka,Bruce R. Blazar,Scott R. Burger,Angela Panoskaltsis-Mortari,Carolyn A. Keever-Taylor,Mei-Jie Zhang,J.S. Miller +10 more
TL;DR: It is concluded that IL-2-activated cells/IL-2 boluses can be safely administered, generate PBMNCs with enhanced cytotoxicity against NK-resistant targets, and increase cytokine levels.