"T2-high" in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin
Stelios Pavlidis,Stelios Pavlidis,Kentaro Takahashi,Francois Ng Kee Kwong,Jiaxing Xie,Uruj Hoda,Kai Sun,V. Elyasigomari,Paul-Michael Agapow,Matthew J. Loza,F. Baribaud,Pascal Chanez,Steve J. Fowler,Dominic E. Shaw,Louise Fleming,Peter H. Howarth,Ana R. Sousa,Julie Corfield,Charles Auffray,Bertrand De Meulder,Richard G. Knowles,Peter J. Sterk,Yike Guo,Ian M. Adcock,Ian M. Adcock,Ratko Djukanovic,Kian Fan Chung,Kian Fan Chung +27 more
TLDR
T2-high severe asthma can be predicted to some extent from raised levels of FeNO, blood and sputum eosinophil counts, but serum IgE or serum periostin were poor predictors and better bedside biomarkers are needed to detect T2- high.Citations
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The Role of Lung and Gut Microbiota in the Pathology of Asthma
TL;DR: This review focuses on recently discovered connections between lung and gut microbiota, including bacteria, fungi, viruses, and archaea, and their influence on asthma.
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Characterization of Severe Asthma Worldwide: Data From the International Severe Asthma Registry.
Eileen Wang,Michael E. Wechsler,Trung N. Tran,Liam G Heaney,Rupert Jones,Andrew Menzies-Gow,John Busby,David A. Jackson,Paul E Pfeffer,Chin Kook Rhee,You Sook Cho,G. Walter Canonica,Enrico Heffler,Peter G. Gibson,Peter G. Gibson,Mark Hew,Matthew J. Peters,Erin S. Harvey,Marianna Alacqua,James Zangrilli,Lakmini Bulathsinhala,Victoria Carter,Isha Chaudhry,Neva Eleangovan,Naeimeh Hosseini,Ruth Murray,David Price +26 more
TL;DR: This study is the first to describe severe asthma characteristics of a large cohort of patients included in multiple severe asthma registries, and to identify country differences.
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Distinct effects of asthma and COPD comorbidity on disease expression and outcome in patients with COVID-19.
Jia Song,Ming Zeng,Hai Wang,Chuan Qin,Hongyan Hou,Ziyong Sun,San-Peng Xu,Guo-Ping Wang,Cui-Lian Guo,Yi-Ke Deng,Zhi-Chao Wang,Jin Ma,Li Pan,Bo Liao,Zhi-Hui Du,Qimiao Feng,Yang Liu,Jun-Gang Xie,Zheng Liu +18 more
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