The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM
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TLDR
A marked increase in the use of international datasets for more highly evidenced-based changes in staging, and the enhanced use of nonanatomic prognostic factors in defining the stage grouping are notable.Abstract:
The American Joint Committee on Cancer and the International Union for Cancer Control update the tumor-node-metastasis (TNM) cancer staging system periodically. The most recent revision is the 7th edition, effective for cancers diagnosed on or after January 1, 2010. This editorial summarizes the background of the current revision and outlines the major issues revised. Most notable are the marked increase in the use of international datasets for more highly evidenced-based changes in staging, and the enhanced use of nonanatomic prognostic factors in defining the stage grouping. The future of cancer staging lies in the use of enhanced registry data standards to support personalization of cancer care through cancer outcome prediction models and nomograms.read more
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ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer
Jian-Kang Zhou,Yu-Zhu Zheng,Xuesha Liu,Qiheng Gou,Rui Ma,Chenglin Guo,Carlo M. Croce,Lunxu Liu,Yong Peng +8 more
TL;DR: It is demonstrated that ROR1 expression is correlated with malignant attributes and may serve as a novel prognostic marker and therapeutic target for colorectal cancer.
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Interobserver agreement of skeletal muscle mass measurement on head and neck CT imaging at the level of the third cervical vertebra
Sandra I. Bril,Anne W. Wendrich,Justin E. Swartz,Inge Wegner,Frank A. Pameijer,Ernst J. Smid,G. H. Bol,Ajit J. Pothen,R. de Bree +8 more
TL;DR: Assessment of SMM at the level of C3 is easy and robust and can performed on routinely available imaging in HNC patients and the Bland–Altman plot showed good agreement between measurements, with narrow limits of agreement.
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Disease‐induced and treatment‐induced alterations in body composition in locally advanced head and neck squamous cell carcinoma
Anna C.H. Willemsen,Ann Hoeben,Roy I. Lalisang,Ardy van Helvoort,Frederik W.R. Wesseling,Frank J. P. Hoebers,Laura W. J. Baijens,Annemie M. W. J. Schols +7 more
TL;DR: The aim of this cohort study was to assess the relationship of fat‐free mass index (FFMI) and handgrip strength (HGS) with CRT/BRT toxicity and outcome, and the effect of the current TF regime on body composition and muscle strength in patients treated with chemoradiation vs. bioradiation.
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Clinical features and prognostic factors in papillary thyroid microcarcinoma depends on age.
Jin-Kyu Cho,Ju-Yeon Kim,Chi-Young Jeong,Eun-Jung Jung,Soon-Tae Park,Sang-Ho Jeong,Young-Tae Ju,Young-Joon Lee,Soon-Chan Hong,Woo-Song Ha,Sang-Kyung Choi +10 more
TL;DR: Clinicians should consider a different strategy for therapy and plan for follow-up according to age in patients with papillary thyroid microcarcinoma according to patients' age.
References
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Book
AJCC Cancer Staging Manual
Mahul B. Amin,Stephen B. Edge,Frederick L. Greene,David R. Byrd,Robert K. Brookland,Mary Kay Washington,Jeffrey E. Gershenwald,Carolyn C. Compton,Kenneth R. Hess,Daniel C. Sullivan,J. Milburn Jessup,James D. Brierley,Lauri E. Gaspar,Richard L. Schilsky,Charles M. Balch,David P. Winchester,Elliot A. Asare,Martin Madera,Donna M. Gress,Laura R. Meyer +19 more
TL;DR: Purposes and Principles of Cancer Staging and End-Results Reporting are explained.
Related Papers (5)
AJCC Cancer Staging Manual
Mahul B. Amin,Stephen B. Edge,Frederick L. Greene,David R. Byrd,Robert K. Brookland,Mary Kay Washington,Jeffrey E. Gershenwald,Carolyn C. Compton,Kenneth R. Hess,Daniel C. Sullivan,J. Milburn Jessup,James D. Brierley,Lauri E. Gaspar,Richard L. Schilsky,Charles M. Balch,David P. Winchester,Elliot A. Asare,Martin Madera,Donna M. Gress,Laura R. Meyer +19 more