The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.Abstract:
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurateread more
Citations
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Journal ArticleDOI
Venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis.
Laveena Munshi,Laveena Munshi,Allan J. Walkey,Ewan C. Goligher,Ewan C. Goligher,Tài Pham,Tài Pham,Elizabeth Uleryk,Eddy Fan,Eddy Fan +9 more
TL;DR: Compared with conventional mechanical ventilation, use of venovenous ECMO in adults with severe acute respiratory distress syndrome was associated with reduced 60-day mortality, however, venovenou ECMO was also associated with a moderate risk of major bleeding.
Journal ArticleDOI
Evaluation of the Cochrane Collaboration’s tool for assessing the risk of bias in randomized trials: focus groups, online survey, proposed recommendations and their implementation
Jelena Savović,Laura Weeks,Jonathan A C Sterne,Lucy Turner,Douglas G. Altman,David Moher,David Moher,Julian P T Higgins,Julian P T Higgins +8 more
TL;DR: Recommendations were made for improvements to the RoB tool and associated guidance and the implementation of these recommendations is currently underway.
Journal ArticleDOI
Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies
Meghan B. Azad,Ahmed M Abou-Setta,Bhupendrasinh F Chauhan,Rasheda Rabbani,Justin Lys,Leslie Copstein,Amrinder Singh Mann,Maya M. Jeyaraman,Ashleigh E. Reid,Michelle Fiander,Dylan S. MacKay,Jon Mcgavock,Brandy Wicklow,Ryan Zarychanski +13 more
TL;DR: Evidence from RCTs does not clearly support the intended benefits of nonnutritive sweeteners for weight management, and observational data suggest that routine intake of non-nutritives may be associated with increased BMI and cardiometabolic risk.
Journal ArticleDOI
Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
Suetonia C. Palmer,Britta Tendal,Reem A. Mustafa,Reem A. Mustafa,Per Olav Vandvik,Sheyu Li,Sheyu Li,Qiukui Hao,David J. Tunnicliffe,Marinella Ruospo,Patrizia Natale,Patrizia Natale,V. Saglimbene,Antonio Nicolucci,David W. Johnson,Marcello Tonelli,Maria Chiara Rossi,Sunil V. Badve,Yeoungjee Cho,Annie-Claire Nadeau-Fredette,Michael Burke,Labib Faruque,Anita Lloyd,Nasreen Ahmad,Yuanchen Liu,Sophanny Tiv,Tanya Millard,Lucia Gagliardi,Nithin Kolanu,Rahul Barmanray,Rita McMorrow,Ana Karina Raygoza Cortez,Heath White,Xiangyang Chen,Xu Zhou,Jiali Liu,Andrea Flores Rodríguez,Alejandro Díaz González-Colmenero,Yang Wang,Ling Li,Surya S. Sutanto,Ricardo Cesar Solis,Fernando Díaz González-Colmenero,Rene Rodriguez-Gutierrez,Michael Walsh,Michael Walsh,Gordon H. Guyatt,Giovanni F.M. Strippoli,Giovanni F.M. Strippoli +48 more
TL;DR: In this paper, the authors evaluated the effect of SGLT-2 inhibitors and GLP-like peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes at varying cardiovascular and renal risk.
Journal ArticleDOI
Direct Oral Anticoagulants in Patients With VTE and Cancer: A Systematic Review and Meta-analysis
TL;DR: DOAs seem to be as effective and safe as conventional treatment for the prevention of VTE in patients with cancer.
References
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Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal Article
Cochrane Handbook for Systematic Reviews of Interventions
Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI
Assessing Risk of Bias in Included Studies
TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI
Systematic reviews in health care: Assessing the quality of controlled clinical trials
TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.