The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.Abstract:
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurateread more
Citations
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American Geriatrics Society abstracted clinical practice guideline for postoperative delirium in older adults
Mary Jordan Samuel,Sharon K. Inouye,Thomas N. Robinson,Caroline Blaum,Jan Busby-Whitehead,Malaz Boustani,Ara A. Chalian,Stacie Deiner,Donna M. Fick,Lisa C. Hutchison,Jason M. Johanning,Mark R. Katlic,James Kempton,Maura Kennedy,Eyal Y. Kimchi,C.Y. Ko,Jacqueline M. Leung,Melissa L. P. Mattison,Sanjay Mohanty,Arvind Nana,Dale M. Needham,Karin J. Neufeld,Holly E. Richter,Sue Radcliff,Christine Weston,Sneeha Patil,Gina Rocco,Jirong Yue,Susan E. Aiello,Marianna Drootin,Elvy Ickowicz,Mary Jordan Samuel +31 more
TL;DR: The goals of this guideline are to decrease delirium severity and duration, ensure patient safety and improve outcomes, and to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the treatment of postoperativedelirium in older adults.
Journal ArticleDOI
Influence of trial sample size on treatment effect estimates: meta-epidemiological study
Agnès Dechartres,Agnès Dechartres,Ludovic Trinquart,Ludovic Trinquart,Isabelle Boutron,Philippe Ravaud +5 more
TL;DR: Treatment effect estimates differed within meta-analyses solely based on trial sample size, with stronger effect estimates seen in small to moderately sized trials than in the largest trials.
Journal ArticleDOI
How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care: Users’ Guides to the Medical Literature
Mohammad Hassan Murad,Victor M. Montori,John P. A. Ioannidis,Roman Jaeschke,Philip J. Devereaux,Kameshwar Prasad,Ignacio Neumann,Alonso Carrasco-Labra,Thomas Agoritsas,Rose Hatala,Maureen O. Meade,Peter C. Wyer,Deborah J. Cook,Gordon H. Guyatt +13 more
TL;DR: When clinicians apply the results of a systematic review or meta-analysis to patient care, they should start by evaluating the credibility of the methods of the systematic review, ie, the extent to which these methods have likely protected against misleading results.
Journal ArticleDOI
Exercise Training in Patients With Heart Failure and Preserved Ejection Fraction Meta-Analysis of Randomized Control Trials
Ambarish Pandey,Akhil Parashar,Dharam J. Kumbhani,Sunil K. Agarwal,Jalaj Garg,Dalane W. Kitzman,Benjamin D. Levine,Mark H. Drazner,Jarett D. Berry +8 more
TL;DR: In this paper, the effects of exercise training on Cardiorespiratory Fitness (CRF), quality of life, and diastolic function in patients with preserved ejection fraction (HFPEF) were evaluated.
Journal ArticleDOI
Adjuvant Chemotherapy for Invasive Bladder Cancer: A 2013 Updated Systematic Review and Meta-Analysis of Randomized Trials
Jeffrey J. Leow,William Martin-Doyle,Padma Sheila Rajagopal,Chirayu G. Patel,Erin M. Anderson,Andrew T. Rothman,Richard J. Cote,Yuksel Urun,Steven L. Chang,Toni K. Choueiri,Joaquim Bellmunt +10 more
TL;DR: An updated and improved meta-analysis of randomized trials provides further evidence of an overall survival and disease-free survival benefit in patients with MIBC receiving adjuvant cisplatin-based chemotherapy after radical cystectomy.
References
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Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal Article
Cochrane Handbook for Systematic Reviews of Interventions
Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI
Assessing Risk of Bias in Included Studies
TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI
Systematic reviews in health care: Assessing the quality of controlled clinical trials
TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.