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Open AccessJournal ArticleDOI

The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials

TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.
Abstract
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate

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Citations
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Cognitive Behavioral Therapy for Insomnia Comorbid With Psychiatric and Medical Conditions: A Meta-analysis

TL;DR: CBT-I is efficacious for improving insomnia symptoms and sleep parameters for patients with comorbid insomnia, and large-scale studies with more rigorous designs to reduce detection and performance bias are needed.
Journal ArticleDOI

Medical masks vs N95 respirators for preventing COVID-19 in healthcare workers: A systematic review and meta-analysis of randomized trials.

TL;DR: Respiratory protective devices are critical in protecting against infection in healthcare workers at high risk of novel 2019 coronavirus disease (COVID‐19).
Journal ArticleDOI

Do interventions designed to support shared decision-making reduce health inequalities? A systematic review and meta-analysis

TL;DR: SDM interventions may be more beneficial to disadvantaged groups than higher literacy/socioeconomic status patients, and given the small sample sizes and variety in the intervention types, study design and quality, those findings should be interpreted with caution.
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Systematic review and meta-analysis of enhanced recovery programmes in surgical patients.

TL;DR: Whether the effect of ERPs on patient outcomes varies across surgical specialties or with the design of individual programmes is investigated.
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Immune-related adverse events for anti-PD-1 and anti-PD-L1 drugs: systematic review and meta-analysis

TL;DR: Organ specific immune-related adverse events are uncommon with anti-PD-1 drugs but the risk is increased compared with control treatments, and general adverse events related to immune activation are largely similar.
References
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Book

Cochrane Handbook for Systematic Reviews of Interventions

TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal ArticleDOI

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI

Assessing Risk of Bias in Included Studies

TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI

Systematic reviews in health care: Assessing the quality of controlled clinical trials

TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.
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