The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.Abstract:
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurateread more
Citations
More filters
Journal ArticleDOI
Dietary Approaches to Stop Hypertension (DASH) Diet and Blood Pressure Reduction in Adults with and without Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Christina Filippou,Costas Tsioufis,Costas Thomopoulos,Costas Mihas,Kyriakos Dimitriadis,Lida I. Sotiropoulou,Christina Chrysochoou,Petros Nihoyannopoulos,Dimitrios Tousoulis +8 more
TL;DR: The adoption of the DASH diet was accompanied by significant BP reduction in adults with and without hypertension, although higher daily sodium intake and younger age enhanced the BP-lowering effect of the intervention.
Journal ArticleDOI
The Value of Preoperative Exercise and Education for Patients Undergoing Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
TL;DR: Overall effect sizes for prehabilitation were small to moderate, and significant improvements were observed in function, quadriceps strength, and length of stay in patients undergoing THA and TKA.
Journal ArticleDOI
Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool children up to the age of 6 years
Jill L Colquitt,Emma Loveman,Claire O'Malley,Liane B. Azevedo,Emma Mead,Lena Al-Khudairy,Louisa Ells,Maria-Inti Metzendorf,Karen Rees +8 more
TL;DR: In trials comparing a multicomponent intervention withusual care, enhanced usual care, or information control, a greater reduction in body mass index (BMI) z score is found in the intervention groups at the end of the intervention, but only the dairy-rich diet maintained this at 36 months' follow-up.
Journal ArticleDOI
The Effects of Early Intervention on Social Communication Outcomes for Children with Autism Spectrum Disorder: A Meta-analysis
TL;DR: The findings of this meta-analysis highlight the need for further research examining specific components of interventions associated with greater and more generalized gains in studies with context-bound outcome measures.
Journal ArticleDOI
Role of gut microbiota in chronic low-grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies
I. van den Munckhof,Alexander Kurilshikov,R. Ter Horst,Niels P. Riksen,Leo A. B. Joosten,Leo A. B. Joosten,Alexandra Zhernakova,Jingyuan Fu,Samuel T. Keating,Mihai G. Netea,Mihai G. Netea,J. de Graaf,Joost H.W. Rutten +12 more
TL;DR: The associations between the microbiome and the inflammasome, the innate immune system, bile acids, gut permeability, the endocannabinoid system and TMAO are discussed.
References
More filters
Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal Article
Cochrane Handbook for Systematic Reviews of Interventions
Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI
Assessing Risk of Bias in Included Studies
TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI
Systematic reviews in health care: Assessing the quality of controlled clinical trials
TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.