The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.Abstract:
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurateread more
Citations
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Journal ArticleDOI
Phosphate-Binding Agents in Adults With CKD: A Network Meta-analysis of Randomized Trials.
Suetonia C. Palmer,Sharon Gardner,Marcello Tonelli,Dimitris Mavridis,David W. Johnson,Jonathan C. Craig,Richard French,Marinella Ruospo,Giovanni F.M. Strippoli,Giovanni F.M. Strippoli +9 more
TL;DR: Iron-based binders show evidence of greater phosphate lowering that warrants further examination in randomized trials, and there is currently no evidence that phosphate-binder treatment reduces mortality compared to placebo in adults with CKD.
Journal ArticleDOI
Effectiveness of Self-Compassion Related Therapies: a Systematic Review and Meta-analysis
TL;DR: In this paper, a systematic review and meta-analysis investigated whether self-compassion-related therapies, including compassion-focussed therapy, mindfulness-based cognitive therapy and acceptance and commitment therapy, are effective in promoting selfcompassion and reducing psychopathology.
Journal ArticleDOI
Anticoagulant and side-effects of protamine in cardiac surgery: a narrative review
TL;DR: The mechanisms underlying the anticoagulant properties and side‐effects of protamine are described, and the impact of protamines dosing on the activated clotting time and point‐of‐care viscoelastic test results are explained.
Journal ArticleDOI
Assessment of phthalates/phthalate alternatives in children's toys and childcare articles: Review of the report including conclusions and recommendation of the Chronic Hazard Advisory Panel of the Consumer Product Safety Commission.
Paul J. Lioy,Russ Hauser,Chris Gennings,Holger M. Koch,Philip E. Mirkes,Bernard A Schwetz,Andreas Kortenkamp +6 more
TL;DR: Risk assessment demonstrated that some phthalates should be permanently banned, removed from the banned list, or remain interim banned, and biomonitoring and toxicology data provided the strongest basis for a mixture risk assessment.
Journal ArticleDOI
Surgical interventions for the treatment of painful neuroma: a comparative meta-analysis
Louis H. Poppler,Rajiv P. Parikh,Miles J. Bichanich,Kelsey A. Rebehn,Carrie Roth Bettlach,Susan E. Mackinnon,Amy M. Moore +6 more
TL;DR: Surgical treatment of neuroma pain was effective in 77% of patients and excision and transposition or neurolysis and coverage were significantly more likely than other operative techniques to result in a meaningful reduction in pain.
References
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Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal Article
Cochrane Handbook for Systematic Reviews of Interventions
Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI
Assessing Risk of Bias in Included Studies
TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI
Systematic reviews in health care: Assessing the quality of controlled clinical trials
TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.