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Open AccessJournal ArticleDOI

The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials

TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.
Abstract
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate

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Journal ArticleDOI

Systematic review and meta-analysis: techniques and a guide for the academic surgeon

TL;DR: The following article aims to summarize to the important features of a thorough and rigorous systematic review or meta-analysis for the surgical literature, and highlight several underused statistical approaches which may yield further interesting insights compared to conventional pair-wise data synthesis techniques.
Journal ArticleDOI

Long-term effects of low-fat diets either low or high in protein on cardiovascular and metabolic risk factors: a systematic review and meta-analysis

TL;DR: According to the present meta-analysis of long-term RCTs, high-protein diets exerted neither specific beneficial nor detrimental effects on outcome markers of obesity, cardiovascular disease or glycemic control, so it seems premature to recommend high- protein diets in the management of overweight and obesity.
Journal ArticleDOI

Efficacy of interventions to combat tobacco addiction: Cochrane update of 2013 reviews

TL;DR: Cochrane systematic review evidence from 2013 suggests that adding mood management to behavioural support may improve cessation outcomes in smokers with current or past depression and strengthens evidence for previous conclusions, including the safety of varenicline and bupropion and the benefits of behavioural support for smoking cessation in pregnancy.
Journal ArticleDOI

Muscle weakness in hip osteoarthritis: a systematic review.

TL;DR: Whether muscles of the affected legs of individuals with unilateral hip OA are weaker, smaller, and more inhibited than those of their contralateral leg and/or the legs of healthy controls is determined.
References
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Book

Cochrane Handbook for Systematic Reviews of Interventions

TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal ArticleDOI

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations

TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI

Assessing Risk of Bias in Included Studies

TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI

Systematic reviews in health care: Assessing the quality of controlled clinical trials

TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.
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