The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TLDR
The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.Abstract:
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurateread more
Citations
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Journal ArticleDOI
Electronic nicotine delivery systems and/or electronic non-nicotine delivery systems for tobacco smoking cessation or reduction: a systematic review and meta-analysis.
Regina El Dib,Regina El Dib,Erica Aranha Suzumura,Elie A. Akl,Elie A. Akl,Huda Gomaa,Arnav Agarwal,Arnav Agarwal,Yaping Chang,Manya Prasad,Vahid Ashoorion,Vahid Ashoorion,Diane Heels-Ansdell,Wasim Maziak,Gordon H. Guyatt +14 more
TL;DR: There is very limited evidence regarding the impact of ENDS or ENNDS on tobacco smoking cessation, reduction or adverse effects: data from RCTs are of low certainty and observational studies of very low certainty.
Journal ArticleDOI
Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials.
Si Qin,Lifan Huang,Jiaojiao Gong,Jiaojiao Gong,Shasha Shen,Shasha Shen,Juan Huang,Juan Huang,Hong Ren,Huaidong Hu,Huaidong Hu +10 more
TL;DR: Turmeric and curcumin may protect patients at risk of CVD through improving serum lipid levels and may be used as a well-tolerated dietary adjunct to conventional drugs.
Journal ArticleDOI
Transcranial direct current stimulation (tDCS) in the treatment of depression: Systematic review and meta-analysis of efficacy and tolerability
TL;DR: The data do not support the use of tDCS in treatment-resistant depression, or as an add-on augmentation treatment, and tDCS may be efficacious for treatment of MDE.
Journal ArticleDOI
Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis.
TL;DR: This meta-analysis shows that antibiotics as the initial treatment for pediatric patients with uncomplicated appendicitis may be feasible and effective without increasing the risk for complications.
Journal ArticleDOI
Saliva as a Candidate for COVID-19 Diagnostic Testing: A Meta-Analysis
László Márk Czumbel,Szabolcs Kiss,Szabolcs Kiss,Nelli Farkas,Iván Mandel,Anita Emoke Hegyi,Ákos Nagy,Zsolt Lohinai,Zsolt Szakács,Péter Hegyi,Martin C. Steward,Martin C. Steward,Gábor Varga +12 more
TL;DR: Saliva tests offer a promising alternative to NPS for COVID-19 diagnosis, however, further diagnostic accuracy studies are needed to improve their specificity and sensitivity.
References
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Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
Journal Article
Cochrane Handbook for Systematic Reviews of Interventions
Journal ArticleDOI
GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Book ChapterDOI
Assessing Risk of Bias in Included Studies
TL;DR: In this paper, the authors propose a new algorithm called 1.8.1.1-2.0-1.8-1/2.8/1/1.
Journal ArticleDOI
Systematic reviews in health care: Assessing the quality of controlled clinical trials
TL;DR: The concept of study quality and the methods used to assess quality are discussed and the methodology for both the assessment of quality and its incorporation into systematic reviews and meta-analysis is discussed.