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Journal ArticleDOI

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

Ora Kedem, +1 more
- 01 Jan 1958 - 
- Vol. 27, Iss: 2, pp 229-246
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.
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This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).

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Citations
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Journal ArticleDOI

Analysis of lymphatic protein flux data III. Use of the nonlinear flux equation to estimate σ and PS

TL;DR: The use of the nonlinear or exact flux equation for determining estimates of the solvent drag reflection coefficient and the permeability-surface area product of the capillary membrane from lymphatic protein and fluid flux rates is introduced.
Journal ArticleDOI

A multiscale modelling approach to understand atherosclerosis formation: A patient-specific case study in the aortic bifurcation:

TL;DR: The results indicate that the model shows potential to predict the majority of the plaque locations, also not predicting regions where plaques are absent, and the promising results from this case study provide a proof of concept that can be applied to a larger patient population.
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Requirements on Models and Models of Active Transport of Ions in Biomembranes

TL;DR: Requirements on models of the active transport of ions in biomembranes have been formulated and a model satisfying the basic requirements has been proposed as an example.
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Transepithelial transport of nonelectrolytes in the rabbit mandibular salivary gland.

TL;DR: Estimates have been obtained of both the permeability coefficients of the gland and the solvent-drag filtration coefficients and the relation between 1−σ and molecular radius suggests that small polar nonelectrolytes and the bulk of the secreted water cross the epithelium via aqueous channels that are approximately 0.8 nm in width.
References
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Journal ArticleDOI

Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.

TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
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Passage of Molecules Through Capillary Walls

TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
Journal ArticleDOI

Permeability of natural membranes

James Frederic Danielli
- 28 Mar 1953 - 
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