Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
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Biophysics of glomerular filtration.
TL;DR: Ongoing work pertains to the nature, location, and efficiency of the barrier to protein sieving, induction of endothelial fenestrae by growth factors from the podocyte, and potential resistance faced by filtrate exiting the subpodocyte space.
Journal ArticleDOI
A more general form of Kedem and Katchalsky's practical equations
TL;DR: In this work, the Kedem and Katchalsky classical equations are transformed into a more general form and the more general equations obtained here are applicable to the description of streams js and Jv generated in the conditions of both good and poor mixing of solutes.
Journal ArticleDOI
Analysis of proteins transmission in vortex flow ultrafilter for mass transfer coefficient
TL;DR: In this paper, BSA and ovalbumin were ultrafiltered through a hydrophilic ultrafiltration membrane with molecular weight cutoff (MWCO) of 100,000 in a vortex flow module and the protein transmission data were carefully analyzed as a function of pressure at different rotational speed of the membrane.
Journal ArticleDOI
Fluorescence dilution technique for measurement of albumin reflection coefficient in isolated glomeruli.
Fan Fan,Chun Cheng Andy Chen,Jin Zhang,Carlos Schreck,Eric A. Roman,Jan M. Williams,Takashi Hirata,Mukut Sharma,Daniel A. Beard,Virginia J. Savin,Richard J. Roman +10 more
TL;DR: The findings indicate that the fluorescence dilution technique can be used to measure σAlb in populations of isolated glomeruli and provides a means to assess the development of glomerular injury in hypertensive and diabetic models.
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Structural peculiarities dominate the turgor pressure response of the marine alga Valonia utricularis upon osmotic challenges.
TL;DR: The pressure response of (plant) cells to osmotic challenges depends on the reflection coefficient, σ, of osmotically active solutes; in Valonia utricularis, �o is significantly reduced by internal (and, to a lesser extent, by external) unstirred layers, protecting the cytoplasm against vacuolar Osmotic fluctuations.
References
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Journal ArticleDOI
Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more