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Journal ArticleDOI

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

Ora Kedem, +1 more
- 01 Jan 1958 - 
- Vol. 27, Iss: 2, pp 229-246
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.
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This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).

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Citations
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Modeling of low-density lipoprotein (LDL) transport in the artery—effects of hypertension

TL;DR: In this article, a robust four-layer model is presented to describe the LDL transport in the arterial wall coupled with the transport in lumen, where the endothelium, intima, internal elastic lamina and media are all treated as macroscopically homogeneous porous media and the volume-averaged porous media equations are employed to model various layers, with Staverman filtration and osmotic reflection coefficients introduced to account for selective permeability of each porous layer to certain solutes.
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Multi-objective optimization of RO desalination plants

TL;DR: In this article, a process optimization method for the design of reverse osmosis (RO) processes is developed for a brackish water reverse oslosis (BWRO) desalination project, for which the optimal design is characterized depending on the economical conditions.
Journal ArticleDOI

Fundamentals of cryobiology in reproductive medicine

TL;DR: The concept of tolerable osmotic excursion of cell volume will be discussed, along with the evidence for a 'pseudo-glassy' state for cells during traditional cryopreservation, and issues of safety and stability ofcryopreserved samples will be set out.
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Mathematical and numerical models for transfer of low-density lipoproteins through the arterial walls: a new methodology for the model set up with applications to the study of disturbed lumenal flow.

TL;DR: This work introduces and discusses several mathematical models, based on partial differential equations, devised to study the coupled transport of macromolecules as low-density lipoproteins in the blood stream and in the arterial walls, and proposes a new methodology to compute the physical parameters needed for the model set up.
References
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Journal ArticleDOI

Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.

TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
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Passage of Molecules Through Capillary Walls

TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
Journal ArticleDOI

Permeability of natural membranes

James Frederic Danielli
- 28 Mar 1953 - 
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