Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
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A rational approach to oocyte cryopreservation
TL;DR: It has been demonstrated that changes in the cryoprotectant type, concentration and temperature of exposure can dramatically affect the extent of cell volume change, and these factors will potentially influence the ability of the cell to survive the stresses experienced during the subsequent stages of theCryopreservation protocol.
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In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles
TL;DR: This review focuses on microfluidic tumor models for characterization of delivery efficacy and toxicity of cancer nanomedicine and in vitro models are useful in modeling specific steps in NP delivery to tumor and characterize NP transport properties and outcomes by systematic variation of physiological conditions.
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Multiscale homogenization for fluid and drug transport in vascularized malignant tissues
TL;DR: A system of differential equations for coupled fluid and drug transport in vascularized (malignant) tissues is derived by a multiscale expansion to provide a theoretical setting for a better understanding of the design of effective anti-cancer therapies.
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Water and nonelectrolytes permeability in mammalian red cell membranes
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Mechanisms of flux decline in skim milk ultrafiltration: A review
TL;DR: In this paper, the authors analyse published observations of concentration polarisation and fouling of relevance to skim milk ultrafiltration to examine the underlying mechanisms of flux decline caused by these two processes.
References
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Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more