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Journal ArticleDOI

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

Ora Kedem, +1 more
- 01 Jan 1958 - 
- Vol. 27, Iss: 2, pp 229-246
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.
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This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).

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Citations
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Book ChapterDOI

Regulation of Brain Volume Under Isosmotic and Anisosmotic Conditions

TL;DR: Volume regulation at the cellular level, apart from its contribution to brain bulk, has not been studied extensively, but analyses of neuronal activity in invertebrate systems provide indirect evidence that maintenance of normal cell volume is essential for a variety of functions.
Journal ArticleDOI

Sieving equations and effective glomerular filtration pressure

TL;DR: Sieving equations assuming a log normal distribution model are less satisfactory for calculating GFP e than those based on the isoporous model, although they provide an excellent alignment of the calculated and the experimental sieving curves over a wide range of molecular sizes.
Journal ArticleDOI

Restricted diffusion in skeletal muscle capillaries in man

TL;DR: The skeletal muscle capillary permeabilities for EDTA51Cr and inulin were measured simultaneously by means of the indicator-diffusion technique in the exercising forearm of nine normal human adults to indicate the existence of restriction to diffusion for smaller hydrophilic molecules over the skeletal musclecapillary membrane.
Journal ArticleDOI

Terminology for mass transport and exchange

TL;DR: This set of terms, symbols, definitions, and units is proposed as a means of clear communication among workers in the physiological, engineering, and physical sciences to provide a setting for quantitative descriptions of physiological transport phenomena.
References
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Journal ArticleDOI

Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.

TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI

Passage of Molecules Through Capillary Walls

TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
Journal ArticleDOI

Permeability of natural membranes

James Frederic Danielli
- 28 Mar 1953 - 
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