Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
Citations
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Cryopreservation of canine spermatozoa: theoretical prediction of optimal cooling rates in the presence and absence of cryoprotective agents.
Sreedhar Thirumala,M.S. Ferrer,Abdul Al-Jarrah,Bruce E. Eilts,Dale L. Paccamonti,Ram V. Devireddy +5 more
TL;DR: The parameters obtained in this study suggest that optimal rates of freezing canine sperm cells ranges from 10 to 30 degrees C/min; these theoretical cooling rates are found to be in close conformity with previously published but empirically determined optimal cooling rates.
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Electrical hemolysis of human and bovine red blood cells.
TL;DR: An interesting finding is that the breakdown voltage, although constant throughout each normally distributed ghost size distribution, increases with increasing mean volume of the ghost populations.
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Permeability of the bovine red cell to glycerol in hyperosmotic solutions at various temperatures.
TL;DR: Estimates ofP based on differences in activities and on the osmotic shock technique are the least subject to error, and the usual irreversible thermodynamic equations to express the flux may be a misleading refinement.
Journal ArticleDOI
Irreversible thermodynamics and frictional models of membrane processes, with particular reference to the cell membrane
J. Dainty,B.Z. Ginzburg +1 more
TL;DR: The transport of solute and water through the conventional lipid-pore model of the cell membrane is treated by the method of irreversible thermodynamics, resulting in simple formulae for the hydraulic conductivity and reflection coefficient of the membrane.
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Constant Cwall ultrafiltration process control
TL;DR: This work investigated a control strategy using constant C w instead of constant transmembrane pressure for ultrafiltration processes and explored three different strategies for such control and evaluated the theoretical and industrial implications for single solute systems.
References
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Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more