Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
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Intestinal passive absorption of water-soluble compounds by sparrows: effect of molecular size and luminal nutrients.
TL;DR: Predictions that absorption of water-soluble probes decreases with increasing molecular size, consistent with movement through effective pores in epithelia, and absorption is enhanced when measured in the presence of luminal nutrients, are tested.
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The effect of dimethylsulfoxide on the water transport response of rat hepatocytes during freezing.
TL;DR: The experimental data showed that less dehydration occurs during freezing at a given rate in the presence of DMSO at temperatures between 0 and -10 degrees C, and the results suggest that close proximity of the experimental cell volume data to the equilibrium volume curve may significantly reduce the efficiency of the curve-fitting process.
Journal ArticleDOI
Heat Transfer in Living Systems: Current Opportunities
Kenneth R. Diller,T. P. Ryan +1 more
TL;DR: Topics covered include factors that distinguish heat transfer in living systems from inanimate systems, application areas in basic research and in clinical diagnosis and therapy, and the projection of where the field is headed and what are likely to be the most fertile opportunities for contributions by members of the heat transfer community.
Journal ArticleDOI
Computer simulation of three-dimensional plaque formation and progression in the carotid artery.
Nenad Filipovic,Zhongzhao Teng,Milos Radovic,Igor Saveljic,Dimitrios I. Fotiadis,Oberdan Parodi +5 more
TL;DR: Determination of plaque location and composition, and computer simulation of progression in time for a specific patient shows a potential benefit for the prediction of disease progression, proving the proof of validity of three-dimensional computer modeling in the evaluation of atherosclerotic plaque burden.
Journal ArticleDOI
Multifaceted transport characteristics of nanomedicine: needs for characterization in dynamic environment.
TL;DR: The multifaceted transport characteristics of NPs and their interaction mechanisms with the tumor microenvironment are discussed and it is illustrated that NPs have highly spatiotemporal and multiscale distribution around tumor.
References
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Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more