Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
Citations
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Journal ArticleDOI
Permeability of connective tissue linings isolated from implanted capsules; implications for interstitial pressure measurements.
H J Granger,A E Taylor +1 more
TL;DR: The ineffectiveness of the leaky capsule lining in transmitting oncotic pressure suggests that under normal conditions the capsule measures interstitial hydrostatic pressure rather than oncotics pressure.
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Volumetric assessment of the capillary filtration coefficient in the cat small intestine
TL;DR: The capillary filtration coefficient of the cat small intestine was measured in four ways; the conventional measurement was compared with the “zero time extrapolation” technique, and with two methods designed to assess the end of the blood volume shift due to venous pressure elevation.
Journal ArticleDOI
Mechanism of Colonic Permeation of Inulin: Is Rat Colon More Permeable Than Small Intestine?
Thomas Y. Ma,Thomas Y. Ma,Daniel Hollander,Richard A. Erickson,Richard A. Erickson,Hao Truong,Hien Nguyen,Pavel Krugliak +7 more
TL;DR: Rat colon is permeable to inulin, a large hydrophilic macromolecule having a molecular weight of 5000 g/mol and a cross-sectional diameter of 15 A (hydration diameter, 20 A), and the higher net colonic permeability may be caused by differences in mucosal surface, permselectivity, solvent drag effect, and differences in net water fluxes of the colon and small intestine.
Journal ArticleDOI
Mechanistic bases for differences in passive absorption.
TL;DR: It is shown using uniform methodology at the whole-animal level that intact, unanesthetized pigeons had significantly higher absorption of l-arabinose and l-rhamnose, two water-soluble compounds used to measure paracellular absorption, than similarly sized laboratory rats.
Journal ArticleDOI
The need for novel cryoprotectants and cryopreservation protocols: Insights into the importance of biophysical investigation and cell permeability.
TL;DR: Understanding the interplay between cells and biophysical properties is important not just for developing new, and better optimised, cryopreservation protocols, but also for broader research into topics such as dehydration and desiccation tolerance, chilling and heat stress, as well as membrane structure and function.
References
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Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more