Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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TLDR
The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
Citations
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Journal ArticleDOI
Comparison of nonelectrolyte permeability patterns in several epithelia.
TL;DR: It is suggested that additional size-restricted permeation pathways by-passing membrane lipid (“pores”) are present in some tissues and smaller or virtually absent in others.
OtherDOI
Renal medullary circulation
TL;DR: The unique anatomy of this vascular bed and the role it plays in transport and countercurrent exchange in the medulla are described and the importance of the renal medullary circulation in the regulation of fluid and electrolyte homeostasis and arterial blood pressure regulation is discussed.
Journal ArticleDOI
Dependence of zonal chondrocyte water transport properties on osmotic environment
TL;DR: Chondrocyte properties can be sensitive to changes in baseline osmolarity, such as those occurring during OA progression and de novo tissue synthesis (increase).
Journal ArticleDOI
Numerical study of two-dimensional multi-layer spacer designs for minimum drag and maximum mass transfer
TL;DR: In this paper, a series of multi-layer spacer designs for use in spiral wound membrane modules are proposed and evaluated via computational fluid dynamics simulations, and the filament diameter to channel height ratio of traditional cylindrical filaments is reduced from 0.6 to 0.4 and one or two layers of elliptical filaments with various attack angles are introduced in the middle region of the channel.
Patent
Cell-type specific methods and devices for the low temperature preservation of the cells of an animal species
TL;DR: In this paper, the authors describe the use of four equations to predict optimal protocols to add or remove cryoprotectant to or from biological cells, which are found with experimental data of the knetic volume change of the cell type to a known concentration and temperature of Cryoprotector.
References
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Journal ArticleDOI
Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more