Journal ArticleDOI
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes
Ora Kedem,Aharon Katchalsky +1 more
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The equations derived here have been applied to various permeability measurements found in the literature, such as the penetration of heavy water into animal cells, permeability of blood vessels, threshold concentration of plasmolysis and relaxation experiments with artificial membranes.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1958-01-01. It has received 1960 citations till now. The article focuses on the topics: Membrane & Permeability (earth sciences).read more
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Book ChapterDOI
Principles of Water and Nonelectrolyte Transport across Membranes
TL;DR: The hypothesis that natural membranes were mosaic structures containing lipids and pores, or molecular sieves, is hypothesized, based on the observations of Overton and Collander and Barlund, and current theories concerning membrane pores depend on this hypothesis.
Journal ArticleDOI
Yeast cell responses to water potential variations
Journal ArticleDOI
Design and characterization of genetically engineered zebrafish aquaporin-3 mutants highly permeable to the cryoprotectant ethylene glycol.
TL;DR: The functional properties of zebrafish GLPs were investigated and two constructs were constructed, one mutant with enhanced ethylene glycol permeability and another with reduced pH sensitivity, which may be useful for application in cryobiology.
Journal ArticleDOI
Gap junctions amplify spatial variations in cell volume in proliferating tumor spheroids
TL;DR: A mechano-osmotic model is proposed to investigate the evolution of volume dynamics within multicellular systems and identifies how gap junctions can amplify spatial variations in cell volume withinMulticellular spheroids and describes how the process depends on proliferation-induced solid stress.
Journal ArticleDOI
Reduction in pulmonary blood volume during positive end-expiratory pressure.
TL;DR: It is concluded that PEEP significantly reduced intravascular pulmonary fluid volumes along with cardiac output, without changing EVLW.
References
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Journal ArticleDOI
Filtration, diffusion and molecular sieving through peripheral capillary membranes; a contribution to the pore theory of capillary permeability.
TL;DR: Theoretical and experimental studies on the sieving of molecules by ultrafiltration through porous membranes indicate that an effective pore diameter of at least IOO A would be required to explain permeability of this magnitude.
Journal ArticleDOI
Passage of Molecules Through Capillary Walls
TL;DR: A wealth of evidence supports the view that the exchange of materials through the walls of living capillaries takes place by physical processes which involve no expenditure of energy on the part of the capillary endothelial cells themselves.
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Thermodynamics of hyperfiltration (reverse osmosis): criteria for efficient membranes
K.S. Spiegler,Ora Kedem +1 more