Journal ArticleDOI
Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers
Apostolis A. Koutinas,Anestis Vlysidis,Daniel Pleissner,Nikolaos Kopsahelis,Isabel Lopez Garcia,Ioannis K. Kookos,Seraphim Papanikolaou,Tsz Him Kwan,Carol Sze Ki Lin +8 more
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TLDR
It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.Abstract:
The transition from a fossil fuel-based economy to a bio-based economy necessitates the exploitation of synergies, scientific innovations and breakthroughs, and step changes in the infrastructure of chemical industry. Sustainable production of chemicals and biopolymers should be dependent entirely on renewable carbon. White biotechnology could provide the necessary tools for the evolution of microbial bioconversion into a key unit operation in future biorefineries. Waste and by-product streams from existing industrial sectors (e.g., food industry, pulp and paper industry, biodiesel and bioethanol production) could be used as renewable resources for both biorefinery development and production of nutrient-complete fermentation feedstocks. This review focuses on the potential of utilizing waste and by-product streams from current industrial activities for the production of chemicals and biopolymers via microbial bioconversion. The first part of this review presents the current status and prospects on fermentative production of important platform chemicals (i.e., selected C2-C6 metabolic products and single cell oil) and biopolymers (i.e., polyhydroxyalkanoates and bacterial cellulose). In the second part, the qualitative and quantitative characteristics of waste and by-product streams from existing industrial sectors are presented. In the third part, the techno-economic aspects of bioconversion processes are critically reviewed. Four case studies showing the potential of case-specific waste and by-product streams for the production of succinic acid and polyhydroxyalkanoates are presented. It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.read more
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Journal ArticleDOI
A mathematical programming formulation for biorefineries technology selection
Nikolaos Bonatsos,Endrit Dheskali,Denise M. G. Freire,Aline Machado de Castro,Apostolis A. Koutinas,Ioannis K. Kookos +5 more
TL;DR: In this article, the authors proposed a mathematical programming methodology to assist decision makers in strategic (long term) planning for bioprocessing of renewable resources, where the design detail of the bi-rocess design was incorporated in the strategic model and the use of a relatively accurate model for estimating the cost of manufacture of the alternative bi-processes.
Journal ArticleDOI
Efficient and Bio-inspired Conversion of Cellulose to Formic Acid Catalyzed by Metalloporphyrins in Alkaline Solution
TL;DR: A bio-inspired approach for efficient conversion of cellulose to formic acid (FA) was developed in an aqueous alkaline medium as mentioned in this paper, where sulfonated iron(III) porphyrin as the catalyst and O2 as the oxidant Iron(III)-peroxo species, TSPPFeIIIOO−, was involved to cleave the C-C bonds of gluconic acid to FA.
Journal ArticleDOI
Comparative assessment of separation techniques for downstream processing of 2,3-Butanediol
TL;DR: In this paper, the reverse osmosis membrane showed potential to separate 2,3-BDO from the actual fermentation broth, and the salting-out method used ammonium sulphate.
Journal ArticleDOI
Cell Retention as a Viable Strategy for PHA Production from Diluted VFAs with Bacillus megaterium
TL;DR: A cell recycle fed-batch system using Bacillus megaterium uyuni S29 for poly(3-hydroxybutyrate) (P3HB) production from acetic acid could contribute to an efficient and sustainable production of biopolymers.
Journal ArticleDOI
A newly isolated Enterobacter sp. strain produces 2,3-butanediol during its cultivation on low-cost carbohydrate-based substrates.
Anastasia Marina Palaiogeorgou,Seraphim Papanikolaou,Aline Machado de Castro,Denise M. G. Freire,Ioannis K. Kookos,Apostolis A. Koutinas +5 more
TL;DR: The newly isolated wild Enterobacter sp.
References
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Cellulose: Fascinating Biopolymer and Sustainable Raw Material
TL;DR: The current knowledge in the structure and chemistry of cellulose, and in the development of innovative cellulose esters and ethers for coatings, films, membranes, building materials, drilling techniques, pharmaceuticals, and foodstuffs are assembled.
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Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited
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Journal ArticleDOI
Recent trends in global production and utilization of bio-ethanol fuel
Mustafa Balat,Havva Balat +1 more
TL;DR: The most widely used bio-fuel for transportation worldwide is bio-ethanol from sugar cane, which is essentially a clean fuel and has several clear advantages over petroleum-derived gasoline in reducing greenhouse gas emissions and improving air quality in metropolitan areas as mentioned in this paper.
Journal ArticleDOI
Characterization and genomic analysis of kraft lignin biodegradation by the beta-proteobacterium Cupriavidus basilensis B-8
TL;DR: These results confirmed the capability of C. basilensis B-8 to promote KL degradation and provide a theoretical basis for research into the mechanisms of lignin degradation as well as a practical basis for biofuel production using lignIn materials.
Journal ArticleDOI
A review of the production of ethanol from softwood
Mats Galbe,Guido Zacchi +1 more
TL;DR: The current status of the technology for ethanol production from softwood is reviewed, with focus on hemicellulose and cellulose hydrolysis, which is the major problem in the overall process.