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Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers

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TLDR
It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.
Abstract
The transition from a fossil fuel-based economy to a bio-based economy necessitates the exploitation of synergies, scientific innovations and breakthroughs, and step changes in the infrastructure of chemical industry. Sustainable production of chemicals and biopolymers should be dependent entirely on renewable carbon. White biotechnology could provide the necessary tools for the evolution of microbial bioconversion into a key unit operation in future biorefineries. Waste and by-product streams from existing industrial sectors (e.g., food industry, pulp and paper industry, biodiesel and bioethanol production) could be used as renewable resources for both biorefinery development and production of nutrient-complete fermentation feedstocks. This review focuses on the potential of utilizing waste and by-product streams from current industrial activities for the production of chemicals and biopolymers via microbial bioconversion. The first part of this review presents the current status and prospects on fermentative production of important platform chemicals (i.e., selected C2-C6 metabolic products and single cell oil) and biopolymers (i.e., polyhydroxyalkanoates and bacterial cellulose). In the second part, the qualitative and quantitative characteristics of waste and by-product streams from existing industrial sectors are presented. In the third part, the techno-economic aspects of bioconversion processes are critically reviewed. Four case studies showing the potential of case-specific waste and by-product streams for the production of succinic acid and polyhydroxyalkanoates are presented. It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.

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Citations
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Mystery behind Chinese liquor fermentation

TL;DR: Wang et al. as mentioned in this paper provided a detailed, systematic and critical review on Chinese liquor to improve the current industrial practice and serve the modern society with yet incompletely explored but useful principles.
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Production of bioplastic through food waste valorization.

TL;DR: This review focuses on current technologies for the production of polyhydroxyalkanoates (PHA) from food waste, with particular attention paid to fermentation technologies based on pure and mixed cultures.
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Producing PHAs in the bioeconomy — Towards a sustainable bioplastic

TL;DR: In this paper, the authors have shown that polyhydroxyalkanoates (PHAs) can contribute to greenhouse gas emission reduction targets, waste reduction as well as green jobs and innovation in the biotechnology sector.
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Bioremediation 3.0: Engineering pollutant-removing bacteria in the times of systemic biology.

TL;DR: In this paper, the authors analyze how contemporary systemic biology is helping to take the design of bioremediation agents back to the core of environmental biotechnology and propose an engineering workflow.
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Bioconversion of biomass waste into high value chemicals.

TL;DR: The valorization of inexpensive, abundantly available, and renewable biomass waste could provide significant benefits in response to increasing fossil fuel demands and manufacturing costs, as well as emerging environmental concerns.
References
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Journal ArticleDOI

Development and evaluation of efficient recombinant Escherichia coli strains for the production of 3‐hydroxypropionic acid from glycerol

TL;DR: The efficiency of the recombinant strain(s) was improved by expressing DhaB and AldH in two compatible isopropyl‐thio‐β‐galactoside inducible plasmids along with glycerol dehydratase reactivase (GDR) and it was found that the changes in protein expression were associated with their enzymatic activity and balance.
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Optimization of L-malic acid production by Aspergillus flavus in a stirred fermentor.

TL;DR: The high molar yields obtained are additional evidence for the operation of part of the reductive branch of the tricarboxylic acid cycle in L‐malic acid accumulation by A. flavus and coincide with increases in the activities of NAD+‐malate dehydrogenase, fumarase, and citrate synthase.
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Effect of different additives on bacterial cellulose production by Acetobacter xylinum and analysis of material property

TL;DR: In this article, different additives including agar, carboxymethylcellulose (CMC), microcrystalline cellulose, and sodium alginate were added into fermentation medium in agitated culture to enhance BC production by Acetobacter xylinum.
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Utilization of residues from agro-forest industries in the production of high value bacterial cellulose

TL;DR: Preliminary results on the addition of other nutrient sources to the residues-based culture media indicated that, in general, these BC productions could be increased by ~200% and ~100% for the crude glycerol and grape skins, respectively, after the addition organic or inorganic nitrogen.
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Biological conversion of wood hydrolysate to succinic acid by Anaerobiospirillum succiniciproducens.

TL;DR: Anaerobiospirillum succiniciproducens grew on a minimal salts medium containing wood hydrolysate and, when supplemented with 10 g corn steep liquor as a complex nitrogen source, succinic acid at 24 g l−1 was obtained (yield = 88% w/w glucose).
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