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Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers

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TLDR
It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.
Abstract
The transition from a fossil fuel-based economy to a bio-based economy necessitates the exploitation of synergies, scientific innovations and breakthroughs, and step changes in the infrastructure of chemical industry. Sustainable production of chemicals and biopolymers should be dependent entirely on renewable carbon. White biotechnology could provide the necessary tools for the evolution of microbial bioconversion into a key unit operation in future biorefineries. Waste and by-product streams from existing industrial sectors (e.g., food industry, pulp and paper industry, biodiesel and bioethanol production) could be used as renewable resources for both biorefinery development and production of nutrient-complete fermentation feedstocks. This review focuses on the potential of utilizing waste and by-product streams from current industrial activities for the production of chemicals and biopolymers via microbial bioconversion. The first part of this review presents the current status and prospects on fermentative production of important platform chemicals (i.e., selected C2-C6 metabolic products and single cell oil) and biopolymers (i.e., polyhydroxyalkanoates and bacterial cellulose). In the second part, the qualitative and quantitative characteristics of waste and by-product streams from existing industrial sectors are presented. In the third part, the techno-economic aspects of bioconversion processes are critically reviewed. Four case studies showing the potential of case-specific waste and by-product streams for the production of succinic acid and polyhydroxyalkanoates are presented. It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.

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Citations
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Production of bioplastic through food waste valorization.

TL;DR: This review focuses on current technologies for the production of polyhydroxyalkanoates (PHA) from food waste, with particular attention paid to fermentation technologies based on pure and mixed cultures.
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Bioremediation 3.0: Engineering pollutant-removing bacteria in the times of systemic biology.

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Bioconversion of biomass waste into high value chemicals.

TL;DR: The valorization of inexpensive, abundantly available, and renewable biomass waste could provide significant benefits in response to increasing fossil fuel demands and manufacturing costs, as well as emerging environmental concerns.
References
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Journal ArticleDOI

Polyhydroxyalkanoates Production From Low-cost Sustainable Raw Materials

TL;DR: In this article, a review of the production of polyhydroxyalkanoates using low-cost sustainable raw materials such as molasses, whey, lignocelluloses, fats and oils, glycerol and wastewater are described.
Journal ArticleDOI

Bacterial Cellulose Production by Fed-Batch Fermentation in Molasses Medium

TL;DR: Batch and fed‐batch fermentations for bacterial cellulose (BC) production using molasses as a carbon source by Acetobacter xylinum BPR2001 were carried out in a jar fermentor and maximum BC concentration was obtained with a feeding rate of 6.3 g‐sugar/h, which was derived from the optimal IFB experiment.
Journal ArticleDOI

Butanol production from wood pulping hydrolysate in an integrated fermentation–gas stripping process

TL;DR: With gas stripping for in situ product removal, ABE production from WPH increased, demonstrating that gas stripping was effective in alleviating butanol toxicity by selectively separating butanol from the fermentation broth, which greatly improved solvents production and sugar conversion in the fermentation.
Journal Article

Current trends in biotechnological production of xylitol and future prospects

TL;DR: This review describes recent research developments on biological conversion of hemicellulosic biomass towards production of xylitol by taking advantage of power of biotechnology and identifies ways forward for improved enzymatic xylitor production to compete with current chemical processes.
Journal ArticleDOI

Microbial production of 2,3-butanediol by a mutagenized strain of Serratia marcescens H30.

TL;DR: A suitable control strategy which combined the respiratory quotient (RQ) control with the constant residual sucrose concentration fed-batch was developed and obtained the maximum 2,3-BD concentration.
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