Journal ArticleDOI
Valorization of industrial waste and by-product streams via fermentation for the production of chemicals and biopolymers
Apostolis A. Koutinas,Anestis Vlysidis,Daniel Pleissner,Nikolaos Kopsahelis,Isabel Lopez Garcia,Ioannis K. Kookos,Seraphim Papanikolaou,Tsz Him Kwan,Carol Sze Ki Lin +8 more
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TLDR
It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.Abstract:
The transition from a fossil fuel-based economy to a bio-based economy necessitates the exploitation of synergies, scientific innovations and breakthroughs, and step changes in the infrastructure of chemical industry. Sustainable production of chemicals and biopolymers should be dependent entirely on renewable carbon. White biotechnology could provide the necessary tools for the evolution of microbial bioconversion into a key unit operation in future biorefineries. Waste and by-product streams from existing industrial sectors (e.g., food industry, pulp and paper industry, biodiesel and bioethanol production) could be used as renewable resources for both biorefinery development and production of nutrient-complete fermentation feedstocks. This review focuses on the potential of utilizing waste and by-product streams from current industrial activities for the production of chemicals and biopolymers via microbial bioconversion. The first part of this review presents the current status and prospects on fermentative production of important platform chemicals (i.e., selected C2-C6 metabolic products and single cell oil) and biopolymers (i.e., polyhydroxyalkanoates and bacterial cellulose). In the second part, the qualitative and quantitative characteristics of waste and by-product streams from existing industrial sectors are presented. In the third part, the techno-economic aspects of bioconversion processes are critically reviewed. Four case studies showing the potential of case-specific waste and by-product streams for the production of succinic acid and polyhydroxyalkanoates are presented. It is evident that fermentative production of chemicals and biopolymers via refining of waste and by-product streams is a highly important research area with significant prospects for industrial applications.read more
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Mystery behind Chinese liquor fermentation
Guangyuan Jin,Yang Zhu,Yan Xu +2 more
TL;DR: Wang et al. as mentioned in this paper provided a detailed, systematic and critical review on Chinese liquor to improve the current industrial practice and serve the modern society with yet incompletely explored but useful principles.
Journal ArticleDOI
Production of bioplastic through food waste valorization.
Yiu Fai Tsang,Vanish Kumar,Pallabi Samadar,Yi Yang,Jechan Lee,Yong Sik Ok,Hocheol Song,Kihyun Kim,Eilhann E. Kwon,Young Jae Jeon +9 more
TL;DR: This review focuses on current technologies for the production of polyhydroxyalkanoates (PHA) from food waste, with particular attention paid to fermentation technologies based on pure and mixed cultures.
Journal ArticleDOI
Producing PHAs in the bioeconomy — Towards a sustainable bioplastic
TL;DR: In this paper, the authors have shown that polyhydroxyalkanoates (PHAs) can contribute to greenhouse gas emission reduction targets, waste reduction as well as green jobs and innovation in the biotechnology sector.
Journal ArticleDOI
Bioremediation 3.0: Engineering pollutant-removing bacteria in the times of systemic biology.
TL;DR: In this paper, the authors analyze how contemporary systemic biology is helping to take the design of bioremediation agents back to the core of environmental biotechnology and propose an engineering workflow.
Journal ArticleDOI
Bioconversion of biomass waste into high value chemicals.
TL;DR: The valorization of inexpensive, abundantly available, and renewable biomass waste could provide significant benefits in response to increasing fossil fuel demands and manufacturing costs, as well as emerging environmental concerns.
References
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Heterotrophic high cell-density fed-batch and continuous flow cultures of Galdieria sulphuraria and production of phycocyanin
TL;DR: Production of biomass and phycocyanin were investigated in highly pigmented variants of the unicellular rhodophyte Galdieria sulphuraria, which maintained high specific pigment concentrations when grown heterotrophically in darkness.
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Metabolic engineering of Corynebacterium glutamicum for production of 1,5‐diaminopentane from hemicellulose
TL;DR: The bio-based production of 1,5-diaminopentane (cadaverine), an important building block for bio-polyamides, was extended to hemicellulose a non-food raw material by engineering the metabolism of Corynebacterium glutamicum to the use of the C(5) sugar xylose.
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Glycerol utilisation for the production of chemicals: conversion to succinic acid, a combined experimental and computational study.
TL;DR: The model developed can be utilised to successfully predict the concentration profiles of the five most important state variables (biomass, glycerol, succinic acid, formic acid, and acetic acid) with different initial Glycerol concentrations and can be further used to compute optimal operating/parametric conditions, which maximise yield, productivity and/or the final succinic Acid concentration.
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Enhanced butyric acid tolerance and bioproduction by Clostridium tyrobutyricum immobilized in a fibrous bed bioreactor.
Ling Jiang,Jufang Wang,Shizhong Liang,Jin Cai,Zhinan Xu,Peilin Cen,Shang-Tian Yang,Shuang Li +7 more
TL;DR: Adapted strains were harvested from the FBB and characterized for their physiological properties, including specific growth rate, acid‐forming enzymes, intracellular pH, membrane‐bound ATPase and cell morphology, and compared with the original culture used to seed the bioreactor, the adapted culture showed significantly reduced inhibition effects of butyric acid.
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Improvement of Bacterial Cellulose Production by Addition of Agar in a Jar Fermentor
TL;DR: Enhanced productivity is associated with an increase in viscosity of the culture, dispersion of BC pellets, and number of free cells due to agar addition, suggesting that acetan produced by BPR 2001 has a critical role in enhanced BC production.