A
Anders Björklund
Researcher at Lund University
Publications - 771
Citations - 87172
Anders Björklund is an academic researcher from Lund University. The author has contributed to research in topics: Transplantation & Dopamine. The author has an hindex of 165, co-authored 769 publications receiving 84268 citations. Previous affiliations of Anders Björklund include University of Washington & Institute for the Study of Labor.
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Long distance axonal growth in the adult central nervous system
TL;DR: Results show that implanted fetal neuroblasts have the capacity to reconstruct specific circuitry over long distances in the lesioned adult brain.
Journal Article
Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism.
Håkan Widner,J Tetrud,S Rehncrona,B J Snow,Patrik Brundin,Anders Björklund,Olle Lindvall,J W Langston +7 more
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α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
TL;DR: It is concluded that α-synuclein pathology in serotonergic or cholinergic neurons alone is not sufficient to impair non-motor behaviors, but that it is their simultaneous involvement that determines severity of such symptoms.
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Grafts of fetal septal cholinergic neurons to the hippocampal formation in aged or fimbria-fornix-lesioned rats.
Anders Björklund,Fred H. Gage +1 more
TL;DR: There are no data so far to implicate an actual loss of cholinergic forebrain neurons with age in rodents, that is, one that would be similar to that experienced in patients with Alzheimer’s disease, but in aged rodents, impairments in learning and memory have been associated with an age-dependent decline in the parameters of forebrain cholinergy transmission.
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Neurotransmitter-related gene expression in intrastriatal striatal transplants. III: Regulation by host cortical and dopaminergic afferents
TL;DR: Results indicate that both cortical and dopaminergic afferents originating in the host, functionally regulate neuropeptide mRNA expression within the striatal grafts, and that the two afferent systems interact with each other in the regulation of enkephalin gene expression in grafted neurons.