A
Anders Björklund
Researcher at Lund University
Publications - 771
Citations - 87172
Anders Björklund is an academic researcher from Lund University. The author has contributed to research in topics: Transplantation & Dopamine. The author has an hindex of 165, co-authored 769 publications receiving 84268 citations. Previous affiliations of Anders Björklund include University of Washington & Institute for the Study of Labor.
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Loss of AChE- and NGFr-labeling precedes neuronal death of axotomized septal-diagonal band neurons: reversal by intraventricular NGF infusion.
Walter Fischer,Anders Björklund +1 more
TL;DR: It is concluded that down-regulation of marker proteins, such as AChE and NGFr, and cellular atrophy precede cell death in the axotomized septohippocampal system and that about 1/3 of the axonia-fornix septal cholinergic neurons may survive for a long time in a down-regulated atrophic state.
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Mechanisms of regrowth of the bulbospinal serotonin system following 5,6-dihydroxytryptamine induced axotomy. I. Biochemical correlates.
Anders Björklund,Leif Wiklund +1 more
TL;DR: The results demonstrate an extensive recovery of the neurotransmitter biosynthetic machinery during regeneration of the chemically axotomized serotonin neurons, suggesting that regional compensatory mechanisms may alleviate the functional consequences of the abnormal distribution of the regenerated terminals.
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Fluorophore formation from catecholamines and related compounds in the glyoxylic acid fluorescence histochemical method
TL;DR: The DOPA fluorophore formed in this combined reaction is proposed to be a fully aromatic isoquinoline, the 2,4-dicarboxymethylisoquinolinium compound, which provides a possibility for the direct histochemical differentiation between DOPA and dopamine by microspectrofluorometry.
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Prefrontal Corticostriatal Afferents Maintain Increased Enkephalin Gene Expression in the Dopamine‐denervated Rat Striatum
TL;DR: In the absence of a functional striatal dopamine input, augmented glutamatergic transmission in corticostriatal afferents is necessary to maintain increased levels of PPE mRNA expression, and hence also enkephalin synthesis, in striatal projection neurons.
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Nigral Transplants Reinnervating the Dopamine-Depleted Neostriatum Can Sustain Intracranial Self-Stimulation
TL;DR: These findings suggest that transplanted dopamine neurons convey specific, temporally organized information axonally to the striatum in rats with brain lesions induced by 6-hydroxydopamine.