Anders Björklund

TL;DR: The results support the conclusion that unilateral reinnervation of the dorsal neostriatum by nigral transplants is capable of inducing recovery in asymmetric motor behavior and posture, in sensory attention on the side contralateral to the transplant, and in sensorimotor orientation in bilaterally lesioned rats.

TL;DR: The results show that the immortalized neural progenitors can differentiate into mature glial cells, including astrocytes, oligodendrocyte and pericytes, after implantation into the adult striatum.

TL;DR: It is concluded that neural tissue transplantation provides a powerful new tool in the study of the functional organization of the hippocampus and its various neurotransmitter‐specific afferent systems.

TL;DR: Based on the available clinical and preclinical data, strategies to avoid GID in future clinical trials using fetal cell transplants or cell preparations derived from stem cells are outlined.

TL;DR: It is shown that cell-intrinsic factors determine graft-derived axonal innervation, whereas synaptic inputs from host neurons primarily reflect the graft location, and that hESC-derived dopaminergic grafts transplanted in a long-term preclinical rat model of Parkinson’s disease receive synaptic input from subtypes of host cortical, striatal, and pallidal neurons.