A
Anders Björklund
Researcher at Lund University
Publications - 771
Citations - 87172
Anders Björklund is an academic researcher from Lund University. The author has contributed to research in topics: Transplantation & Dopamine. The author has an hindex of 165, co-authored 769 publications receiving 84268 citations. Previous affiliations of Anders Björklund include University of Washington & Institute for the Study of Labor.
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Book ChapterDOI
The integration and function of striatal grafts.
TL;DR: The degree of observed recovery following experimental striatal destruction has provided a major stimulus for considering whether a similar strategy may be of clinical application in human neurological disease, in particular ones involving striatal neurodegeneration, of which the prototypical example is Huntington's disease.
Journal ArticleDOI
Intracerebral grafting of dopamine neurons. Experimental basis for clinical trials in patients with Parkinson's disease
Patrik Brundin,Robert E. Strecker,Olle Lindvall,Ole Isacson,Ola Nilsson,Gilles Barbin,Alain Prochiantz,Claudia Forni,André Nieoullon,Håkan Widner,Fred H. Gage,Anders Björklund +11 more
Journal ArticleDOI
Mode and mechanism of action of neurotoxic indoleamines: a review and a progress report
H. G. Baumgarten,H. P. Klemm,Lutz Lachenmayer,Anders Björklund,W. Lovenberg,H. G. Schlossberger +5 more
TL;DR: The need for a less generally cytotoxic serotonin neurotoxin was thus clearly evident, and in 1972 Baumgarten and Lachenmayer described the effects of intraventricular administration of 5,7dihydroxytryptamine (5,7-DHT) on central 5-HT neurons by use of the conventional Falck-Hillarp method.
Journal ArticleDOI
Axon outgrowth from grafts of human embryonic spinal cord in the lesioned adult rat spinal cord.
Klas Wictorin,Anders Björklund +1 more
TL;DR: Adult rats with acute partial lesions of their upper thoracic spinal cords were implanted bilaterally with cell suspensions of 6-7 week-old embryonic human spinal cord tissue one segment above or below the lesions, and extensive efferent projections were demonstrated extending longitudinally from the grafts into the host spinal cord.
Journal ArticleDOI
Fetal striatal neurons grafted into the ibotenate lesioned adult striatum: Efferent projections and synaptic contacts in the host globus pallidus
TL;DR: The results show that grafted fetal striatal neurons can grow along the myelinated territory of the internal capsule to reinstate a seemingly normal synaptic input to the previously denervated neurons in the host globus pallidus.