Anders Björklund

TL;DR: The potential of intracerebral grafts to induce or improve behavioral recovery in brain-damaged recipients rests on the multitude of trophic, neurohumoral and synaptic mechanisms that may allow the implanted tissue to promote host brain function and repair.

TL;DR: It is proposed that this apparent dopaminergic hyperinnervation from the graft could provide a powerful inhibition of the cholinergic interneurons in the reinnervated host striatum, and that such an inhibitory mechanism could assist in the graft-induced functional recovery by potentiating the functional effects of DA synapses terminating on the spiny efferent neurons.

TL;DR: The results show that developmental pathways play key roles for the maintenance of terminally differentiated neurons and suggest that disrupted function of Nurr1 and other developmental transcription factors may contribute to neurodegenerative disease.

TL;DR: Impairment in learning and/or memory performance in the aged rats, as assessed in the Morris' water‐maze task, was significantly correlated with both cholinergic cell size and cell number in the medial septum, and with cholinesterase‐positive neurons in the diagonal band of Broca and in the striatum.

TL;DR: In this paper, the authors summarize and evaluate recent empirical research on education and family background, focusing on two related but distinct motivations for this topic: equality of opportunity and the child development perspective.