A
Andrew Zimmer
Researcher at Broad Institute
Publications - 20
Citations - 7207
Andrew Zimmer is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome & Genomics. The author has an hindex of 11, co-authored 20 publications receiving 6744 citations.
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Journal ArticleDOI
An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.
Marc P. Hoeppner,Andrew L. Lundquist,Andrew L. Lundquist,Mono Pirun,Jennifer R. S. Meadows,Neda Zamani,Jeremy Johnson,Görel Sundström,April Cook,Michael Fitzgerald,Ross Swofford,Evan Mauceli,Behrooz Torabi Moghadam,Anna Greka,Jessica Alföldi,Amr Abouelleil,Lynne Aftuck,Daniel Bessette,Aaron M. Berlin,Adam Brown,Gary Gearin,Annie Lui,Pendexter Macdonald,Margaret Priest,Terrance Shea,Jason Turner-Maier,Andrew Zimmer,Eric S. Lander,Federica Di Palma,Federica Di Palma,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh,Manfred Grabherr,Manfred Grabherr +33 more
TL;DR: An improved genome build, canFam3.1, is presented and a much-improved annotation of the canine genome is provided and regulatory functions for several of the novel non-coding transcripts are suggested.
Journal ArticleDOI
A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454
Niall J. Lennon,Robert E. Lintner,Scott Anderson,Pablo Alvarez,Andrew Barry,William Brockman,Riza M. Daza,Rachel L. Erlich,Georgia Giannoukos,Lisa Green,Andrew Hollinger,Cindi A. Hoover,David B. Jaffe,Frank Juhn,Danielle McCarthy,Danielle Perrin,Karen Ponchner,Taryn L Powers,Kamran Rizzolo,Dana Robbins,Elizabeth M. Ryan,Carsten Russ,Todd Sparrow,John Stalker,Scott Steelman,Michael Weiand,Andrew Zimmer,Matthew R. Henn,Chad Nusbaum,Robert Nicol +29 more
TL;DR: An automated, high throughput library construction process for 454 technology, where one technician can create 96 sequence-ready 454 libraries in 2 days, a dramatic improvement over the standard method.
Journal ArticleDOI
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage
Michael C. Zody,Manuel Garber,David J. Adams,Ted Sharpe,Jennifer Harrow,James R. Lupski,Christine Nicholson,S. Searle,Laurens G. Wilming,Sarah Young,Amr Abouelleil,Nicole R. Allen,Weimin Bi,Toby Bloom,Mark L. Borowsky,Boris Bugalter,Jonathan Butler,Jean L. Chang,Chao-Kung Chen,April Cook,Benjamin Corum,Christina A. Cuomo,Pieter J. de Jong,David DeCaprio,Ken Dewar,Ken Dewar,Michael Fitzgerald,James G. R. Gilbert,Richard Gibson,Sante Gnerre,Steven A. Goldstein,Darren Grafham,Russell J. Grocock,Nabil Hafez,Daniel S. Hagopian,E. Hart,Catherine Hosage Norman,Sean Humphray,David B. Jaffe,Matthew C. Jones,Michael Kamal,Varsha K. Khodiyar,Kurt LaButti,Gavin K. Laird,Jessica A. Lehoczky,Xiaohong Liu,Tashi Lokyitsang,Jane E. Loveland,Annie Lui,Pendexter Macdonald,John E. Major,John E. Major,Lucy Matthews,Evan Mauceli,Steven A. McCarroll,Atanas Mihalev,Jonathan M. Mudge,Cindy Nguyen,Robert Nicol,Sinéad B. O'Leary,Kazutoyo Osoegawa,David C. Schwartz,Charles Shaw-Smith,Pawel Stankiewicz,Charles A. Steward,David Swarbreck,Vijay Venkataraman,Charles A. Whittaker,Charles A. Whittaker,Xiaoping Yang,Andrew Zimmer,Allan Bradley,Tim Hubbard,Bruce W. Birren,Jane Rogers,Eric S. Lander,Chad Nusbaum +76 more
TL;DR: Examination of the main classes of duplicated segments provides insight into the dynamics underlying expansion of chromosome-specific, low-copy repeats in the human genome.
Journal ArticleDOI
Human chromosome 11 DNA sequence and analysis including novel gene identification
Todd D. Taylor,Hideki Noguchi,Yasushi Totoki,Atsushi Toyoda,Yoko Kuroki,Ken Dewar,Ken Dewar,Christine Lloyd,Takehiko Itoh,Tadayuki Takeda,Dae-Won Kim,Xinwei She,K F Barlow,Toby Bloom,Elspeth A. Bruford,Jean L. Chang,Christina A. Cuomo,Evan E. Eichler,Michael Fitzgerald,David B. Jaffe,Kurt LaButti,Robert Nicol,Hong Seog Park,Christopher Seaman,Carrie Sougnez,Xiaoping Yang,Andrew Zimmer,Michael C. Zody,Bruce W. Birren,Chad Nusbaum,Asao Fujiyama,Masahira Hattori,Jane Rogers,Eric S. Lander,Yoshiyuki Sakaki +34 more
TL;DR: The high-quality data presented here—nearly 134.5 million base pairs representing 99.8% coverage of the euchromatic sequence—provide scientists with a solid foundation for understanding the genetic basis of these disorders and other biological phenomena.
Journal ArticleDOI
Analysis of the DNA sequence and duplication history of human chromosome 15
Michael C. Zody,Manuel Garber,Ted Sharpe,Sarah Young,Lee Rowen,Keith O'Neill,Charles A. Whittaker,Michael Kamal,Jean L. Chang,Christina A. Cuomo,Ken Dewar,Michael Fitzgerald,Chinnappa D. Kodira,Anup Madan,Shizhen Qin,Xiaoping Yang,Nissa Abbasi,Amr Abouelleil,Harindra Arachchi,Lida Baradarani,Brian Birditt,Scott Bloom,Toby Bloom,Mark L. Borowsky,Jeremy Burke,Jonathan Butler,April Cook,Kurt DeArellano,David DeCaprio,Lester Dorris,Monica Dors,Evan E. Eichler,Reinhard Engels,Jessica Fahey,Peter Fleetwood,Cynthia Friedman,Gary Gearin,Jennifer L. Hall,Grace Hensley,Ericka M. Johnson,Charlien Jones,Asha Kamat,Amardeep Kaur,Devin P. Locke,Anuradha Madan,Glen Munson,David B. Jaffe,Annie Lui,Pendexter Macdonald,Evan Mauceli,Jerome Naylor,Ryan Nesbitt,Robert Nicol,Sinéad B. O'Leary,Amber L Ratcliffe,Steven Rounsley,Xinwei She,Katherine M. B. Sneddon,Sandra Stewart,Carrie Sougnez,Sabrina M. Stone,Kerri Topham,Dascena Vincent,Shunguang Wang,Andrew Zimmer,Bruce W. Birren,Leroy Hood,Eric S. Lander,Chad Nusbaum +68 more
TL;DR: A detailed analysis of the duplication structure of human chromosome 15 finds that most of the intrachromosomal duplications seem to share a common ancestry, and demonstrates that some remaining gaps in the genome sequence are probably due to structural polymorphisms between haplotypes.