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Arthur M. Butt

Researcher at University of Portsmouth

Publications -  157
Citations -  9017

Arthur M. Butt is an academic researcher from University of Portsmouth. The author has contributed to research in topics: Oligodendrocyte & Myelin. The author has an hindex of 48, co-authored 148 publications receiving 7593 citations. Previous affiliations of Arthur M. Butt include East Carolina University & Guy's Hospital.

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Reactive astrocyte nomenclature, definitions, and future directions

Carole Escartin, +88 more
- 15 Feb 2021 - 
TL;DR: In this article, the authors point out the shortcomings of binary divisions of reactive astrocytes into good-vs-bad, neurotoxic vs-neuroprotective or A1-vs.A2.
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Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study.

TL;DR: The increase in electrical resistance at birth indicates a decrease in paracellular ion permeability at the blood‐brain barrier and is required for effective brain interstitial fluid ion regulation.
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Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration

TL;DR: Axon regeneration is arrested in the injured central nervous system (CNS) by axon growth-inhibitory ligands expressed in oligodendrocytes/myelin, NG2-glia, and reactive astrocyte in the lesion and degenerating tracts, and by fibroblasts in scar tissue.
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Inwardly rectifying potassium channels (Kir) in central nervous system glia: a special role for Kir4.1 in glial functions.

TL;DR: It is proposed that Kir4.1 have a primary function in K+ regulation, both as homomeric channels and as heteromersic channels by co‐assembley with Kir5.1 and probably Kir2.0 subtypes.
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P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system

TL;DR: The results implicate ATP as a primary signalling molecule in glial cells and indicate specific roles for P2Y and P2X purinoceptors inglial cell pathology.