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Benjamin F.J. Verhaaren
Researcher at Erasmus University Rotterdam
Publications - 30
Citations - 2181
Benjamin F.J. Verhaaren is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Population & Hyperintensity. The author has an hindex of 20, co-authored 27 publications receiving 1857 citations. Previous affiliations of Benjamin F.J. Verhaaren include Erasmus University Medical Center.
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Journal ArticleDOI
Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study.
Elisabeth M. C. Schrijvers,Benjamin F.J. Verhaaren,Peter J. Koudstaal,Albert Hofman,M. A. Ikram,Monique M.B. Breteler +5 more
TL;DR: This study suggests that dementia incidence has decreased between 1990 and 2005, and participants in 2005–2006 had larger total brain volumes and less cerebral small vessel disease than participants in 1995–1996.
Journal ArticleDOI
Common variants at 12q14 and 12q24 are associated with hippocampal volume
Joshua C. Bis,Charles DeCarli,Albert V. Smith,Fedde van der Lijn,Fabrice Crivello,Fabrice Crivello,Myriam Fornage,Stephanie Debette,Stephanie Debette,Joshua M. Shulman,Joshua M. Shulman,Helena Schmidt,Velandai Srikanth,Velandai Srikanth,Maaike Schuur,Lei Yu,Seung Hoan Choi,Sigurdur Sigurdsson,Benjamin F.J. Verhaaren,Anita L. DeStefano,Jean-Charles Lambert,Clifford R. Jack,Maksim Struchalin,Jim Stankovich,Carla A. Ibrahim-Verbaas,Debra A. Fleischman,Alex P. Zijdenbos,Tom den Heijer,Bernard Mazoyer,Bernard Mazoyer,Laura H. Coker,Christian Enzinger,Patrick Danoy,Najaf Amin,Konstantinos Arfanakis,Konstantinos Arfanakis,Mark A. van Buchem,Renée F A G de Bruijn,Alexa S. Beiser,Carole Dufouil,Juebin Huang,Margherita Cavalieri,Russell Thomson,Wiro J. Niessen,Wiro J. Niessen,Lori B. Chibnik,Lori B. Chibnik,Gauti Kjartan Gislason,Albert Hofman,Aleksandra Pikula,Philippe Amouyel,Kevin B. Freeman,Thanh G. Phan,Ben A. Oostra,Jason L. Stein,Sarah E. Medland,Sarah E. Medland,Alejandro Arias Vasquez,Derrek P. Hibar,Margaret J. Wright,Barbara Franke,Nicholas G. Martin,Paul M. Thompson,Mike A. Nalls,André G. Uitterlinden,Rhoda Au,Alexis Elbaz,Richard Beare,Richard Beare,John C. van Swieten,Oscar L. Lopez,Tamara B. Harris,Vincent Chouraki,Monique M.B. Breteler,Monique M.B. Breteler,Monique M.B. Breteler,Philip L. De Jager,Philip L. De Jager,James T. Becker,Meike W. Vernooij,David S. Knopman,Franz Fazekas,Philip A. Wolf,Aad van der Lugt,Vilmundur Gudnason,William T. Longstreth,Matthew A. Brown,David A. Bennett,Cornelia M. van Duijn,Cornelia M. van Duijn,Thomas H. Mosley,Reinhold Schmidt,Christophe Tzourio,Christophe Tzourio,Lenore J. Launer,M. Arfan Ikram,Sudha Seshadri +96 more
TL;DR: In this article, a genome-wide association study (GWAS) of dementia-free persons (n = 9,232) identified 46 SNPs at four loci with P values of <4.0 × 10(-7).
Journal ArticleDOI
Changes in Normal-Appearing White Matter Precede Development of White Matter Lesions
Marius de Groot,Benjamin F.J. Verhaaren,Renske de Boer,Stefan Klein,Albert Hofman,Aad van der Lugt,M. Arfan Ikram,Wiro J. Niessen,Meike W. Vernooij +8 more
TL;DR: White matter changes in NAWM are present and can be quantified on diffusion tensor imaging and FLAIR before WML develop, suggesting that WML development gradually, and that visually appreciable WML are only the tip of the iceberg of white matter pathology.
Journal ArticleDOI
High Blood Pressure and Cerebral White Matter Lesion Progression in the General Population
Benjamin F.J. Verhaaren,Meike W. Vernooij,Renske de Boer,Albert Hofman,Wiro J. Niessen,Aad van der Lugt,M. Arfan Ikram +6 more
TL;DR: High blood pressure is established to precede WMLs and implies that hypertension treatment could reduce WML progression in the general population, as well as evaluating whether treatment of hypertension is related to less W ML progression.
Journal ArticleDOI
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.
Elizabeth G. Holliday,Jane Maguire,Jane Maguire,Tiffany-Jane Evans,Simon A. Koblar,Simon A. Koblar,Jim Jannes,Jim Jannes,Jonathan Sturm,Graeme J. Hankey,Graeme J. Hankey,Ross I. Baker,Ross I. Baker,Jonathan Golledge,Jonathan Golledge,Mark W Parsons,Rainer Malik,Mark McEvoy,Erik Biros,Martin Lewis,Lisa F. Lincz,Roseanne Peel,Christopher Oldmeadow,Wayne Smith,Pablo Moscato,Simona Barlera,Steve Bevan,Joshua C. Bis,Eric Boerwinkle,Giorgio B. Boncoraglio,Thomas G. Brott,Robert D. Brown,Yu-Ching Cheng,John W. Cole,John W. Cole,Ioana Cotlarciuc,William J. Devan,William J. Devan,Myriam Fornage,Karen L. Furie,Solveig Gretarsdottir,Andreas Gschwendtner,M. Arfan Ikram,W. T. Longstreth,James F. Meschia,Braxton D. Mitchell,Thomas H. Mosley,Mike A. Nalls,Eugenio Parati,Bruce M. Psaty,Bruce M. Psaty,Pankaj Sharma,Kari Stefansson,Kari Stefansson,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Matthew Traylor,Benjamin F.J. Verhaaren,Kerri L. Wiggins,Bradford B. Worrall,Catherine Sudlow,Peter M. Rothwell,Martin Farrall,Martin Dichgans,Jonathan Rosand,Jonathan Rosand,Hugh S. Markus,Rodney J. Scott,Christopher Levi,John Attia +70 more
TL;DR: This study identifies a genetic risk locus for LAA and shows how analyzing etiological subtypes may better identify genetic risk alleles for ischemic stroke.