R
Renée F A G de Bruijn
Researcher at Erasmus University Medical Center
Publications - 7
Citations - 710
Renée F A G de Bruijn is an academic researcher from Erasmus University Medical Center. The author has contributed to research in topics: Cognitive decline & Rotterdam Study. The author has an hindex of 6, co-authored 7 publications receiving 620 citations. Previous affiliations of Renée F A G de Bruijn include Erasmus University Rotterdam.
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Journal ArticleDOI
Common variants at 12q14 and 12q24 are associated with hippocampal volume
Joshua C. Bis,Charles DeCarli,Albert V. Smith,Fedde van der Lijn,Fabrice Crivello,Fabrice Crivello,Myriam Fornage,Stephanie Debette,Stephanie Debette,Joshua M. Shulman,Joshua M. Shulman,Helena Schmidt,Velandai Srikanth,Velandai Srikanth,Maaike Schuur,Lei Yu,Seung Hoan Choi,Sigurdur Sigurdsson,Benjamin F.J. Verhaaren,Anita L. DeStefano,Jean-Charles Lambert,Clifford R. Jack,Maksim Struchalin,Jim Stankovich,Carla A. Ibrahim-Verbaas,Debra A. Fleischman,Alex P. Zijdenbos,Tom den Heijer,Bernard Mazoyer,Bernard Mazoyer,Laura H. Coker,Christian Enzinger,Patrick Danoy,Najaf Amin,Konstantinos Arfanakis,Konstantinos Arfanakis,Mark A. van Buchem,Renée F A G de Bruijn,Alexa S. Beiser,Carole Dufouil,Juebin Huang,Margherita Cavalieri,Russell Thomson,Wiro J. Niessen,Wiro J. Niessen,Lori B. Chibnik,Lori B. Chibnik,Gauti Kjartan Gislason,Albert Hofman,Aleksandra Pikula,Philippe Amouyel,Kevin B. Freeman,Thanh G. Phan,Ben A. Oostra,Jason L. Stein,Sarah E. Medland,Sarah E. Medland,Alejandro Arias Vasquez,Derrek P. Hibar,Margaret J. Wright,Barbara Franke,Nicholas G. Martin,Paul M. Thompson,Mike A. Nalls,André G. Uitterlinden,Rhoda Au,Alexis Elbaz,Richard Beare,Richard Beare,John C. van Swieten,Oscar L. Lopez,Tamara B. Harris,Vincent Chouraki,Monique M.B. Breteler,Monique M.B. Breteler,Monique M.B. Breteler,Philip L. De Jager,Philip L. De Jager,James T. Becker,Meike W. Vernooij,David S. Knopman,Franz Fazekas,Philip A. Wolf,Aad van der Lugt,Vilmundur Gudnason,William T. Longstreth,Matthew A. Brown,David A. Bennett,Cornelia M. van Duijn,Cornelia M. van Duijn,Thomas H. Mosley,Reinhold Schmidt,Christophe Tzourio,Christophe Tzourio,Lenore J. Launer,M. Arfan Ikram,Sudha Seshadri +96 more
TL;DR: In this article, a genome-wide association study (GWAS) of dementia-free persons (n = 9,232) identified 46 SNPs at four loci with P values of <4.0 × 10(-7).
Journal ArticleDOI
The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study
Renée F A G de Bruijn,Michiel J. Bos,Marileen L.P. Portegies,Albert Hofman,Oscar H. Franco,Peter J. Koudstaal,M. Arfan Ikram +6 more
TL;DR: Although prevention and treatment options of cardiovascular risk factors and diseases have improved, the preventive potential for dementia has not declined over the last two decades.
Journal ArticleDOI
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study
Sara Hägg,Sara Hägg,Sara Hägg,Tove Fall,Tove Fall,Tove Fall,Alexander Ploner,Reedik Mägi,Krista Fischer,Harmen H.M. Draisma,Mart Kals,Paul S. de Vries,Abbas Dehghan,Sara M. Willems,Antti-Pekka Sarin,Antti-Pekka Sarin,Kati Kristiansson,Marja-Liisa Nuotio,Aki S. Havulinna,Renée F A G de Bruijn,M. Arfan Ikram,Maris Kuningas,Bruno H. Stricker,Oscar H. Franco,Beben Benyamin,Christian Gieger,Alistair S. Hall,Ville Huikari,Antti Jula,Marjo-Riitta Järvelin,Marika Kaakinen,Jaakko Kaprio,Michael Kobl,Massimo Mangino,Christopher P. Nelson,Aarno Palotie,Nilesh J. Samani,Tim D. Spector,David P. Strachan,Martin D. Tobin,John Whitfield,André G. Uitterlinden,Veikko Salomaa,Ann-Christine Syvänen,Ann-Christine Syvänen,Kari Kuulasmaa,Patrik K. E. Magnusson,Tõnu Esko,Albert Hofman,Eco J. C. de Geus,Lars Lind,Vilmantas Giedraitis,Markus Perola,Alun Evans,Jean Ferrières,Jarmo Virtamo,Frank Kee,David-Alexandre Trégouët,Dominique Arveiler,Philippe Amouyel,Francesco Gianfagna,Paolo Brambilla,Samuli Ripatti,Cornelia M. van Duijn,Andres Metspalu,Inga Prokopenko,Mark I. McCarthy,Nancy L. Pedersen,Erik Ingelsson +68 more
TL;DR: In this paper, the effect of body mass index (BMI) on risk of cardiovascular diseases was investigated using Mendelian randomization (MR) methods, and the results indicated a strong association between BMI and incident coronary heart disease (CHD), heart failure, and ischaemic stroke.
Journal ArticleDOI
Determinants, MRI Correlates, and Prognosis of Mild Cognitive Impairment: The Rotterdam Study
Renée F A G de Bruijn,Saloua Akoudad,Lotte G.M. Cremers,Albert Hofman,Wiro J. Niessen,Aad van der Lugt,Peter J. Koudstaal,Meike W. Vernooij,M. Arfan Ikram +8 more
TL;DR: It was found that several vascular risk factors and MRI-correlates of cerebrovascular disease were related to MCI in the general population and participants with MCI had an increased risk of dementia, including Alzheimer's disease, and mortality.
Featured Article Trajectories of decline in cognition and daily functioning in preclinical dementia
Vincentius J.A. Verlinden,Jos N. van der Geest,Renée F A G de Bruijn,Albert Hofman,Peter J. Koudstaal,M. Arfan Ikram +5 more
TL;DR: Investigation of trajectories of cognition and daily functioning in preclinical dementia, during 18 years of follow‐up, finds clear trends in decline in cognition and day-to-day functioning.