C
Catharina Lavebratt
Researcher at Karolinska University Hospital
Publications - 188
Citations - 8212
Catharina Lavebratt is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Bipolar disorder & Population. The author has an hindex of 40, co-authored 167 publications receiving 6030 citations. Previous affiliations of Catharina Lavebratt include Royal Institute of Technology & Karolinska Institutet.
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Journal ArticleDOI
Variations in FKBP5 and BDNF genes are suggestively associated with depression in a Swedish population-based cohort
TL;DR: Data from a large well-characterized longitudinal population-based sample of adult Swedes with data on life situation and life history support previous reports on FKBP5:rs1360780 and show a gender difference and show involvement of environmental stress.
Journal ArticleDOI
Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression.
Philippe A. Melas,Maria Rogdaki,Andreas Lennartsson,Karl Björk,Hongshi Qi,Anna Witasp,Martin Werme,Gregers Wegener,Aleksander A. Mathé,Per Svenningsson,Catharina Lavebratt +10 more
TL;DR: In this paper, the prefrontal cortex of the Flinders Sensitive Line (FSL) genetic rodent model of depression was found to be hypermethylated after chronic administration of escitalopram (a selective serotonin reuptake inhibitor; SSRI).
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Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
Azmeraw T. Amare,Klaus Oliver Schubert,Klaus Oliver Schubert,Liping Hou,Scott R. Clark,Sergi Papiol,Urs Heilbronner,Urs Heilbronner,Franziska Degenhardt,Fasil Tekola-Ayele,Yi-Hsiang Hsu,Yi-Hsiang Hsu,Tatyana Shekhtman,Mazda Adli,Nirmala Akula,Kazufumi Akiyama,Raffaella Ardau,Bárbara Arias,Jean-Michel Aubry,Lena Backlund,Abesh Kumar Bhattacharjee,Frank Bellivier,Antonio Benabarre,Susanne Bengesser,Joanna M. Biernacka,Armin Birner,Clara Brichant-Petitjean,Pablo Cervantes,Hsi-Chung Chen,Caterina Chillotti,Sven Cichon,Sven Cichon,Cristiana Cruceanu,Piotr M. Czerski,Nina Dalkner,Alexandre Dayer,Maria Del Zompo,J. Raymond DePaulo,Bruno Etain,Peter Falkai,Andreas J. Forstner,Andreas J. Forstner,Andreas J. Forstner,Louise Frisén,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Sébastien Gard,Julie Garnham,Fernando S. Goes,Maria Grigoroiu-Serbanescu,Paul Grof,Ryota Hashimoto,Joanna Hauser,Stefan Herms,Stefan Herms,Per Hoffmann,Per Hoffmann,Andrea Hofmann,Stéphane Jamain,Esther Jiménez,Jean-Pierre Kahn,Layla Kassem,Po-Hsiu Kuo,Tadafumi Kato,John R. Kelsoe,Sarah Kittel-Schneider,Sebastian Kliwicki,Barbara König,Ichiro Kusumi,Gonzalo Laje,Mikael Landén,Mikael Landén,Catharina Lavebratt,Marion Leboyer,Susan G. Leckband,Alfonso Tortorella,Mirko Manchia,Mirko Manchia,Lina Martinsson,Michael McCarthy,Michael McCarthy,Susan L. McElroy,Francesc Colom,Marina Mitjans,Marina Mitjans,Francis M. Mondimore,Palmiero Monteleone,Palmiero Monteleone,Caroline M. Nievergelt,Markus M. Nöthen,Tomas Novak,Claire O'Donovan,Norio Ozaki,Urban Ösby,Andrea Pfennig,James B. Potash,Andreas Reif,Eva Z. Reininghaus,Guy A. Rouleau,Janusz K. Rybakowski,Martin Schalling,Peter R. Schofield,Peter R. Schofield,Barbara W. Schweizer,Giovanni Severino,Paul D. Shilling,Katzutaka Shimoda,Christian Simhandl,Claire Slaney,Alessio Squassina,Thomas Stamm,Pavla Stopkova,Mario Maj,Gustavo Turecki,Eduard Vieta,Julia Volkert,Stephanie H. Witt,Adam Wright,Peter P. Zandi,Philip B. Mitchell,Michael Bauer,Martin Alda,Marcella Rietschel,Francis J. McMahon,Thomas G. Schulze,Bernhard T. Baune +126 more
TL;DR: Evidence is provided for a negative association between high genetic loading for SCZ and poor response to lithium in patients with BPAD, suggesting the potential for translational research aimed at personalized prescribing of lithium.
Journal ArticleDOI
Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene
TL;DR: The data support the antidepressant efficacy of HDACis and suggest that their epigenetic effects may also include DNA methylation changes that are mediated by demethylation-facilitating enzymes like TET1.
Journal ArticleDOI
Kv1.1 channels act as mechanical brake in the senses of touch and pain.
Jizhe Hao,Françoise Padilla,Mathieu Dandonneau,Catharina Lavebratt,Florian Lesage,Jacques Noël,Patrick Delmas +6 more
TL;DR: A mechanosensitive (MS) K(+) current (IKmech) that governs mechanical threshold and adaptation of distinct populations of mechanoreceptors is identified and Mechanosensitivity is attributed to Kv1.1 subunits, through facilitation of voltage-dependent open probability.