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Chris Sander

Researcher at Harvard University

Publications -  730
Citations -  273726

Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.

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By structure predictions sequence-structure gap

TL;DR: The problem of accurately predicting protein three-dimensional structure from sequence has yet to be solved, but several new and promising methods that work in one, two, or three dimensions have invigorated the field and led to further improvements of prediction methods.
Journal ArticleDOI

Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Esther Rheinbay, +93 more
- 16 Feb 2023 - 

On the use of sequence homologies Identical pentapeptides can have cc (cooperativity/protein folding/amino acid sequence homology)

TL;DR: The structural significance of short sequence homologies is investigated by searching proteins of known three-dimensional structure for subsequence identities by finding an identical pentapeptide sequence between two pro- teins, which is not a significant indication of structural similarity or of evolutionary kinship.
Posted ContentDOI

3D RNA from evolutionary couplings

TL;DR: A global statistical sequence probability model of co-variation in a pairs of nucleotide positions to detect 3D contacts is used, in analogy to recently developed breakthrough methods for computational protein folding, to help shed light on the structure and function of non-protein-coding RNAs as well as 3D-structured mRNAs.