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Chris Sander

Researcher at Harvard University

Publications -  730
Citations -  273726

Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.

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Journal ArticleDOI

Globin fold in a bacterial toxin

Liisa Holm, +1 more
- 28 Jan 1993 - 
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Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma

TL;DR: It is found that integrin-α10 promotes tumor cell survival through activation of TRIO-RAC-RICTOR-mTOR signaling, and that inhibitors of RAC and mTOR have antitumor effects in vivo, thus identifying a potential treatment strategy for patients with high-risk myxofibrosarcoma.
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Search for new non-resonant phenomena in high-mass dilepton final states with the ATLAS detector

Georges Aad, +2992 more
TL;DR: In this paper, the first search for non-resonant signals in dielectron and dimuon final states in the mass range above 2 TeV was presented. But the search was restricted to the case of dielectric dielectrons.
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Homology of the NifS family of proteins to a new class of pyridoxal phosphate‐dependent enzymes

Christos A. Ouzounis, +1 more
- 10 May 1993 - 
TL;DR: Based on the detected homology, it is predicted that NifS has also a pyridoxal phosphate‐dependent serine (or related) aminotransferase function associated with nitrogen economy and/or protection during nitrogen fixation.
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Thermitase, a thermostable subtilisin: Comparison of predicted and experimental structures and the molecular cause of thermostability

TL;DR: Based on a combination of theoretical and experimental evidence, the unusually tight binding of calcium by thermitase emerges as the most likely single influence responsible for its increased thermostability.