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Chris Sander

Researcher at Harvard University

Publications -  730
Citations -  273726

Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.

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Ricci Curvature and Robustness of Cancer Networks

Allen Tannenbaum, +7 more
- 16 Feb 2015 - 
TL;DR: In this article, the authors focus on the role of curvature for certain key cancer networks in order to quantitatively indicate their apparent functional robustness relative to their normal counterparts, and show that robustness is closely connected to network entropy which, in turn, is very closely related to curvature.
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Sequence co-evolution gives 3D contacts and structures of protein complexes

Thomas A. Hopf, +6 more
- 06 May 2014 - 
TL;DR: In this paper, the authors present a new generalized method showing that patterns of evolutionary sequence changes across proteins reflect residues that are close in space, and with sufficient accuracy to determine the three-dimensional structure of the protein complexes.
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Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy

Elisa Oricchio, +16 more
- 30 Jun 2014 - 
TL;DR: CDK4 activation/RB phosphorylation occurs in 50% of indolent but high-risk follicular lymphomas and implies susceptibility to dual CDK4 and BCL2 inhibition.
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A Drosophila hsp70 gene contains long, antiparallel, coupled open reading frames (LAC ORFs) conserved in homologous loci.

Irene Konstantopoulou, +6 more
- 01 Oct 1995 - 
TL;DR: Computational analysis shows that this LAC ORF arrangement is conserved in other hsp70 loci in a wide range of organisms, raising questions about possible evolutionary benefits of such a peculiar genomic organization.
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Search for Displaced Leptons in sqrt[s]=13 TeV pp Collisions with the ATLAS Detector.

Georges Aad, +2847 more
- 27 Jul 2021 - 
TL;DR: This search provides unique sensitivity to long-lived scalar supersymmetric lepton partners (sleptons) for lifetimes of 0.1 ns, drastically improving on the previous best limits from LEP.