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Chris Sander

Researcher at Harvard University

Publications -  730
Citations -  273726

Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.

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Time to recurrence and survival in serous ovarian tumors predicted from integrated genomic profiles.

TL;DR: A prediction tool that inputs genomic profiles of primary surgical samples and generates patient-specific predictions for the time to recurrence and survival, along with outcome risk predictions and a prognostic index for patient risk stratification is provided.
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Search for heavy ZZ resonances in the l(+) l(-) l(+) l(-) and l(+) l(-) nu(nu)over-bar final states using proton-proton collisions at root s=13 TeV with the ATLAS detector

Morad Aaboud, +2889 more
TL;DR: In this paper, a search for heavy resonances decaying into a pair of bosons leading to the final states, where $$\ell $$¯¯ stands for either an electron or a muon, is presented.
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Frequent Alterations and Epigenetic Silencing of Differentiation Pathway Genes in Structurally Rearranged Liposarcomas

TL;DR: Multimodality sequence analysis of DLPS revealed recurrent mutations and epigenetic abnormalities critical to liposarcomagenesis and to the suppression of adipocyte differentiation, revealing an unanticipated role for methylation abnormalities in DLPS tumors and suggesting demethylating agents as potential therapeutics.
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Polarity as a criterion in protein design

TL;DR: This work has developed a test by deriving quantities with approximately constant value for all globular proteins, based on empirical analysis of the exposed and buried surfaces of 128 structurally known proteins, which shows the characteristic quantities that best appear to segregate badly designed or deliberately misfolded proteins from their properly folded natural relatives.