C
Chris Sander
Researcher at Harvard University
Publications - 730
Citations - 273726
Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.
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Identification of microRNAs of the herpesvirus family
Sébastien Pfeffer,Alain Sewer,Mariana Lagos-Quintana,Robert L. Sheridan,Chris Sander,Friedrich A. Grässer,Linda F. van Dyk,C. Kiong Ho,C. Kiong Ho,Stewart Shuman,Minchen Chien,James J. Russo,Jingyue Ju,Glenn Randall,Brett D. Lindenbach,Charles M. Rice,Viviana Simon,David D. Ho,Mihaela Zavolan,Thomas Tuschl +19 more
TL;DR: To identify other miRNA genes in pathogenic viruses, a new miRNA gene prediction method with small-RNA cloning from several virus-infected cell types was combined and predicted miRNAs in several large DNA viruses.
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Evaluating cell lines as tumour models by comparison of genomic profiles
TL;DR: The results indicate that the gap between cell lines and tumours can be bridged by genomically informed choices of cell line models for all tumour types.
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Protein 3D structure computed from evolutionary sequence variation.
Debora S. Marks,Lucy J. Colwell,Robert L. Sheridan,Thomas A. Hopf,Andrea Pagnani,Riccardo Zecchina,Chris Sander +6 more
TL;DR: Surprisingly, it is found that the strength of these inferred couplings is an excellent predictor of residue-residue proximity in folded structures, and the top-scoring residue couplings are sufficiently accurate and well-distributed to define the 3D protein fold with remarkable accuracy.
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Pathway Commons, a web resource for biological pathway data
Ethan Cerami,Benjamin Gross,Emek Demir,Igor Rodchenkov,Özgün Babur,Nadia Anwar,Nikolaus Schultz,Gary D. Bader,Chris Sander +8 more
TL;DR: A web-based interface that enables biologists to browse and search a comprehensive collection of pathways from multiple sources represented in a common language, a download site that provides integrated bulk sets of pathway information in standard or convenient formats and a web service that software developers can use to conveniently query and access all data.
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A series of PDB related databases for everyday needs.
Robbie P. Joosten,Tim A. H. te Beek,Elmar Krieger,Maarten L. Hekkelman,Rob Hooft,Reinhard Schneider,Chris Sander,Gert Vriend +7 more
TL;DR: A series of databases that run parallel to the Protein Data Bank, used for the analysis of properties of protein structures in areas ranging from structural genomics, to cancer biology and protein design, are presented.