scispace - formally typeset
J

John F. Pearson

Researcher at University of Otago

Publications -  173
Citations -  7198

John F. Pearson is an academic researcher from University of Otago. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 35, co-authored 163 publications receiving 4788 citations. Previous affiliations of John F. Pearson include St. George's University & Beth Israel Deaconess Medical Center.

Papers
More filters
Journal ArticleDOI

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Mike A. Nalls, +248 more
- 01 Dec 2019 - 
TL;DR: These data provide the most comprehensive survey of genetic risk within Parkinson's disease to date, providing a biological context for these risk factors, and showing that a considerable genetic component of this disease remains unidentified.
Journal ArticleDOI

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

Hunna J. Watson, +258 more
- 01 Aug 2019 - 
TL;DR: The genetic architecture of anorexia nervosa mirrors its clinical presentation, showing significant genetic correlations with psychiatric disorders, physical activity, and metabolic (including glycemic), lipid and anthropometric traits, independent of the effects of common variants associated with body-mass index.
Journal ArticleDOI

The genetic architecture of the human cerebral cortex

Katrina L. Grasby, +359 more
- 20 Mar 2020 - 
TL;DR: Results support the radial unit hypothesis that different developmental mechanisms promote surface area expansion and increases in thickness and find evidence that brain structure is a key phenotype along the causal pathway that leads from genetic variation to differences in general cognitive function.
Journal ArticleDOI

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Raymond K. Walters, +171 more
- 26 Nov 2018 - 
TL;DR: The largest genome-wide association study to date of DSM-IV-diagnosed AD found loci associated with AD and characterized the relationship between AD and other psychiatric and behavioral outcomes, underscoring the genetic distinction between pathological and nonpathological drinking behaviors.
Journal ArticleDOI

Association Between Fine Particulate Matter and Diabetes Prevalence in the U.S.

TL;DR: PM2.5 may contribute to increased diabetes prevalence in the adult U.S. population, an association that persisted after controlling for diabetes risk factors, and add to the growing evidence that air pollution is a risk factor for diabetes.