F
Fjoralba Zeka
Researcher at Ghent University
Publications - 12
Citations - 547
Fjoralba Zeka is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & microRNA. The author has an hindex of 8, co-authored 11 publications receiving 489 citations.
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Journal ArticleDOI
The need for transparency and good practices in the qPCR literature
Stephen A. Bustin,Vladimir Benes,Jeremy A. Garson,Jan Hellemans,Jim F. Huggett,Mikael Kubista,Reinhold Mueller,Tania Nolan,Michael W. Pfaffl,Gregory L. Shipley,Carl T. Wittwer,Peter Schjerling,Philip J. R. Day,Mónica Abreu,Begoña Aguado,Jean-François Beaulieu,Anneleen Beckers,Sara Bogaert,John A. Browne,Fernando Carrasco-Ramiro,Liesbeth Ceelen,Kate L. Ciborowski,Pieter Cornillie,Stephanie Coulon,Ann Cuypers,Sara De Brouwer,Leentje De Ceuninck,Jurgen De Craene,Hélène De Naeyer,Ward De Spiegelaere,Kato Deckers,Annelies Dheedene,Kaat Durinck,Margarida Ferreira-Teixeira,Annelies Fieuw,Jack M. Gallup,Sandra Gonzalo-Flores,Karen Goossens,Femke Heindryckx,Elizabeth Herring,Hans Hoenicka,Laura Icardi,Rolf Jaggi,Farzad Javad,Michael Karampelias,Frederick S. B. Kibenge,Molly J. T. Kibenge,Candy Kumps,Irina Lambertz,Tim Lammens,Amelia Markey,Peter Messiaen,Evelien Mets,Sofia Morais,Alberto Mudarra-Rubio,Justine K. Nakiwala,Hilde Nelis,Pål A. Olsvik,Claudina Perez-Novo,Michelle Plusquin,Tony Remans,Ali Rihani,Paulo Rodrigues-Santos,Pieter Rondou,Rebecca Sanders,Katharina Schmidt-Bleek,Kerstin Skovgaard,Karen Smeets,Laura Tabera,Stefan Toegel,Tim Van Acker,Wim Van den Broeck,Joni Van der Meulen,Mireille Van Gele,Gert Van Peer,Mario Van Poucke,Nadine Van Roy,Sarah Vergult,Joris Wauman,Marina Tshuikina-Wiklander,Erik Willems,Sara Zaccara,Fjoralba Zeka,Jo Vandesompele +83 more
TL;DR: Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information.
Journal ArticleDOI
miRBase Tracker: keeping track of microRNA annotation changes
Gert Van Peer,Steve Lefever,Jasper Anckaert,Anneleen Beckers,Ali Rihani,Alan Van Goethem,Pieter-Jan Volders,Fjoralba Zeka,Maté Ongenaert,Pieter Mestdagh,Jo Vandesompele +10 more
TL;DR: MiRBase Tracker is developed, an easy-to-use online database that keeps track of all historical and current miRNA annotation present in the miRBase database, and is expected to increase the transparency and annotation accuracy in the field of miRNA research.
Journal ArticleDOI
miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples
Katleen De Preter,Pieter Mestdagh,Joëlle Vermeulen,Fjoralba Zeka,Arlene Naranjo,Isabella Bray,Victoria Castel,Caifu Chen,Elżbieta Drożyńska,Angelika Eggert,Michael D. Hogarty,Ewa Izycka-Swieszewska,Wendy B. London,Rosa Noguera,Marta Piqueras,Kenneth Bryan,Benjamin Schowe,Peter van Sluis,Jan J. Molenaar,Alexander Schramm,Johannes H. Schulte,Raymond L. Stallings,Rogier Versteeg,Genevieve Laureys,Nadine Van Roy,Frank Speleman,Jo Vandesompele +26 more
TL;DR: A robust miRNA classifier is established and validated, able to identify a cohort of high-risk NB patients at greater risk for adverse outcome using both fresh frozen and archived material.
Journal ArticleDOI
Straightforward and sensitive RT-qPCR based gene expression analysis of FFPE samples
Fjoralba Zeka,Katrien Vanderheyden,Els De Smet,Claude Cuvelier,Pieter Mestdagh,Jo Vandesompele +5 more
TL;DR: It is concluded that gene-specific reverse transcription and targeted cDNA preamplification are adequate methods for accurate and sensitive RT-qPCR based gene expression analysis of FFPE material.
Journal ArticleDOI
Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients
Fjoralba Zeka,Anneleen Decock,Alan Van Goethem,Katrien Vanderheyden,Fleur Demuynck,Tim Lammens,Tim Lammens,Hetty Helsmoortel,Joëlle Vermeulen,Rosa Noguera,Ana P. Berbegall,Valérie Combaret,Gudrun Schleiermacher,Genevieve Laureys,Genevieve Laureys,Alexander Schramm,Johannes H. Schulte,Johannes H. Schulte,Johannes H. Schulte,Sven Rahmann,Julie Bienertova Vasku,Pavel Mazánek,Marta Jeison,Shifra Ash,Michael D. Hogarty,Mirthala Moreno-Smith,Eveline Barbieri,Jason M. Shohet,Frank Berthold,Tom Van Maerken,Frank Speleman,Matthias Fischer,Matthias Fischer,Katleen De Preter,Pieter Mestdagh,Jo Vandesompele +35 more
TL;DR: Evaluation of serum miRNA variance in a model testing for tumor stage, MYCN status, age at diagnosis, and overall survival revealed tumor stage as the most significant factor impacting miRNA abundance in neuroblastoma serum.