G
Gernot Marx
Researcher at RWTH Aachen University
Publications - 323
Citations - 8497
Gernot Marx is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Intensive care & Medicine. The author has an hindex of 39, co-authored 280 publications receiving 6266 citations. Previous affiliations of Gernot Marx include University of Liverpool & University of Jena.
Papers
More filters
Journal ArticleDOI
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.
Kianoush Kashani,Ali Al-Khafaji,Thomas Ardiles,Antonio Artigas,Sean M. Bagshaw,Max Bell,Azra Bihorac,Robert H. Birkhahn,Cynthia M. Cely,Lakhmir S. Chawla,Danielle Davison,Thorsten Feldkamp,Lui G. Forni,Michelle N. Gong,Kyle J. Gunnerson,Michael Haase,James Hackett,Patrick M. Honore,Eric Hoste,Olivier Joannes-Boyau,Michael Joannidis,Patrick K. Kim,Jay L. Koyner,Daniel T. Laskowitz,Matthew Lissauer,Gernot Marx,Peter A. McCullough,Scott Mullaney,Marlies Ostermann,Thomas Rimmelé,Nathan I. Shapiro,Andrew D. Shaw,Jing Shi,Amy M Sprague,Jean Louis Vincent,Christophe Vinsonneau,Ludwig Wagner,Michael G. Walker,R. Gentry Wilkerson,Kai Zacharowski,John A. Kellum +40 more
TL;DR: Two novel markers for AKI have been identified and validated in independent multicenter cohorts and are superior to existing markers, provide additional information over clinical variables and add mechanistic insight into AKI.
Journal ArticleDOI
Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study
Christian Karagiannidis,Carina Mostert,Corinna Hentschker,Thomas Voshaar,Jürgen Malzahn,Gerhard Schillinger,Jürgen Klauber,Uwe Janssens,Gernot Marx,Steffen Weber-Carstens,Stefan Kluge,Michael Pfeifer,Linus Grabenhenrich,Tobias Welte,Reinhard Busse +14 more
TL;DR: In the German health-care system, in which hospital capacities have not been overwhelmed by the COVID-19 pandemic, mortality has been high for patients receiving mechanical ventilation, particularly for patients aged 80 years or older and those requiring dialysis, and has been considerably lower for patients younger than 60 years.
Journal ArticleDOI
Chemokine (C-C motif) receptor 2–positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury
Jana C. Mossanen,Oliver Krenkel,Can Ergen,Olivier Govaere,Anke Liepelt,Tobias Puengel,Felix Heymann,Sandra Kalthoff,Eric Lefebvre,Dirk Eulberg,Tom Luedde,Gernot Marx,Christian P. Strassburg,Tania Roskams,Christian Trautwein,Frank Tacke +15 more
TL;DR: Human livers of ALF patients requiring liver transplantation reveal increased CD68+ hepatic macrophage numbers with massive infiltrates of periportal CCR2+ macrophages that display a proinflammatory polarization, and the pharmacological inhibition of either CCL2 or C CR2 might bear therapeutic potential by reducing the inflammatory reaction during the early phase of AILI.
Journal ArticleDOI
The Characteristics of 50 Hospitalized COVID-19 Patients With and Without ARDS.
Michael Dreher,Alexander Kersten,Johannes Bickenbach,Paul Balfanz,Bojan Hartmann,Christian Cornelissen,Ayham Daher,Robert Stöhr,Michael Kleines,Sebastian Lemmen,J.C. Brokmann,Tobias Müller,Dirk Müller-Wieland,Gernot Marx,Nikolaus Marx +14 more
TL;DR: This initial description of a cohort of COVID-19 patients with and without ARDS in Germany reveals that those with ARDS more commonly have preexisting respiratory diseases and obesity, as well as persistently elevated inflammatory markers.
Journal ArticleDOI
Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial.
Frank Bloos,Evelyn Trips,Axel Nierhaus,Josef Briegel,Daren K. Heyland,Ulrich Jaschinski,Onnen Moerer,Andreas Weyland,Gernot Marx,Matthias Gründling,Stefan Kluge,Ines Kaufmann,Klaus Ott,Michael Quintel,Florian Jelschen,Patrick Meybohm,Sibylle Rademacher,Andreas Meier-Hellmann,Stefan Utzolino,Udo Kaisers,Christian Putensen,Gunnar Elke,Maximilian Ragaller,Herwig Gerlach,Katrin Ludewig,Michael Kiehntopf,Holger Bogatsch,Christoph Engel,Frank M. Brunkhorst,Markus Loeffler,Konrad Reinhart +30 more
TL;DR: Neither high-dose intravenous administration of sodium selenite nor anti-infectious therapy guided by a procalcitonin algorithm was associated with an improved outcome in patients with severe sepsis.