J
James J. Collins
Researcher at Massachusetts Institute of Technology
Publications - 700
Citations - 105255
James J. Collins is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Synthetic biology & Population. The author has an hindex of 151, co-authored 669 publications receiving 89476 citations. Previous affiliations of James J. Collins include Baylor College of Medicine & University at Albany, SUNY.
Papers
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A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host
Jiarong Gao,Ning Yang,Fred A. Lewis,Peter M. Yau,James J. Collins,Jonathan V. Sweedler,Phillip A. Newmark +6 more
TL;DR: The purification and chemical characterization of Schistosome Paralysis Factor (SPF), a novel tetracyclic alkaloid produced by the rotifer Rotaria rotatoria, are reported, showing that this compound paralyzes schistosomes cercariae and prevents infection, and does so more effectively than analogous compounds.
Journal ArticleDOI
A critical review and meta-analysis of epidemiology studies of occupationally exposed styrene workers evaluated for chromosomal aberration incidence.
James J. Collins,Martha M. Moore +1 more
TL;DR: A meta-analysis of occupational styrene exposed workers and incidence of chromosome aberrations finds insufficient evidence to support a conclusion that styrene exposure increases chromosome aberration frequencies in styrene workers.
Patent
Engineered post-poly a signal rna and uses thereof
TL;DR: In this paper, an engineered nucleic acid encoding a post-poly A signal RNA 3' to a terminator for expression of protein, and/or non-coding RNA.
Patent
Dna-responsive hydrogels, methods of altering a property of a hydrogel, and applications thereof
James J. Collins,Helena de Puig Guixe,Luis Ruben Soenksen Martinez,Max A English,Raphael V. Gayet,Nicolaas M. Angenent-Mari,Angelo S. Mao,Peter Q. Nguyen +7 more
TL;DR: In this article, a polynucleotide-based structural component of a hydrogel is described and methods of altering a property of the hydrogels based on user-defined nucleic acid input sequences are described.
Editing Engagement: Visions of Science, Democracy, and Responsibility in Gene Editing Discourse
TL;DR: In this paper , the authors investigate how ideas of the right relationships among science, the public, and collective decision-making about science and technology come to be envisioned in constructions of public engagement.