J
James J. Collins
Researcher at Massachusetts Institute of Technology
Publications - 700
Citations - 105255
James J. Collins is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Synthetic biology & Population. The author has an hindex of 151, co-authored 669 publications receiving 89476 citations. Previous affiliations of James J. Collins include Baylor College of Medicine & University at Albany, SUNY.
Papers
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CNS tumors and exposure to acrylonitrile: inconsistency between experimental and epidemiology studies.
TL;DR: The epidemiology evidence indicates that acrylonitrile is not a potent CNS tumorigen, and several explanations for the inconsistency between animal and human findings are discussed.
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“Intrinsic” elimination rate and dietary intake estimates for selected indicator PCBs: Toxicokinetic modeling using serial sampling data in US subjects, 2005–2010
TL;DR: Estimates for both elimination half-life and ongoing intake rates for this congener are highly uncertain because of the uncertainty in the changes in measured concentrations and body weights.
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Quantifying Uncertainty in a Risk Assessment Using Human Data
William E. Fayerweather,James J. Collins,A. Robert Schnatter,F. Terry Hearne,Reo A. Menning,Daniel P. Reynefr +5 more
TL;DR: The paper demonstrates that distributional risk assessment is readily adapted to situations in which epidemiologic data serve as the basis for potency estimates and to identify and quantify important sources of uncertainty.
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Chaos and graphicsVisualizing the effects of filtering chaotic signals
TL;DR: It is shown that lowpass filters can induce a nonuniform convergence to a dynamical system's mean state-space location with chaotic attractors, which distorts the attractor's normal geometrical configuration such that the observed system acquires increased dimensionality.
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RNA-responsive elements for eukaryotic translational control.
Evan M. Zhao,Angelo S. Mao,Angelo S. Mao,Helena de Puig,Helena de Puig,Kehan Zhang,Kehan Zhang,Nathaniel D. Tippens,Nathaniel D. Tippens,Xiao Tan,F Ann Ran,Isaac Han,Isaac Han,Peter Q. Nguyen,Emma J. Chory,Emma J. Chory,Tiffany Y Hua,Pradeep Ramesh,David B. Thompson,David B. Thompson,Crystal Yuri Oh,Eric S Zigon,Max A English,James J. Collins +23 more
TL;DR: In this paper, eukaryotic toehold switches (eToeholds) are used as modular riboregulators to discriminate among viral infection status, presence or absence of gene expression and cell types.