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James J. Collins

Researcher at Massachusetts Institute of Technology

Publications -  700
Citations -  105255

James J. Collins is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Synthetic biology & Population. The author has an hindex of 151, co-authored 669 publications receiving 89476 citations. Previous affiliations of James J. Collins include Baylor College of Medicine & University at Albany, SUNY.

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Unraveling the physiological complexities of antibiotic lethality.

TL;DR: This review focuses on a less well-understood aspect of antibiotic action: the complex metabolic events that occur subsequent to the interaction of antibiotics with their molecular targets and play roles in antibiotic lethality.
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Social Reproduction in Classrooms and Schools

TL;DR: The authors discusses the emergence and development of social reproduction analyses of education and examines three main perspectives on reproduction: economic, cultural, and linguistic, arguing that schools are not institutions of equal opportunity but mechanisms for perpetuating social inequalities.
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The redundant nature of locomotor optimization laws

TL;DR: A sagittal-plane model of the lower limb, which considered the possibility of antagonistic and synergistic muscle action and took account of the load-bearing roles of the cruciate ligaments, was applied to a dynamic analysis of level walking, predicted remarkably similar patterns of muscle activity over the gait cycle.
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Designing microbial consortia with defined social interactions.

TL;DR: In this article, the development of synthetic communities through social interaction engineering that combines modular pathway reconfiguration with model creation is presented, where six two-strain consortia are created, each possessing a unique mode of interaction, including commensalism, amensalisms, neutralism, cooperation, competition and predation.
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A modular network for legged locomotion

TL;DR: It is shown that the standard gaits of a quadruped, including walk, trot and pace, cannot all be realized by a single four-cell network without introducing unwanted conjugacies that imply a dynamic equivalence between these gaits that seems inconsistent with observations.