J
James J. Collins
Researcher at Massachusetts Institute of Technology
Publications - 700
Citations - 105255
James J. Collins is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Synthetic biology & Population. The author has an hindex of 151, co-authored 669 publications receiving 89476 citations. Previous affiliations of James J. Collins include Baylor College of Medicine & University at Albany, SUNY.
Papers
More filters
Journal ArticleDOI
Lymphatic and hematopoietic cancers among benzene-exposed workers
TL;DR: The results for all leukemias are consistent with a small increase in risk observed in the lower-exposed subgroups of the Pliofilm study; however, the results are also consistent with no increased risk especially for acute nonlymphocytic leukemia.
Journal ArticleDOI
A systems biology pipeline identifies regulatory networks for stem cell engineering.
Melissa A. Kinney,Melissa A. Kinney,Melissa A. Kinney,Linda T. Vo,Linda T. Vo,Jenna M. Frame,Jenna M. Frame,Jenna M. Frame,Jessica Barragan,Jessica Barragan,Ashlee J. Conway,Ashlee J. Conway,Shuai Li,Shuai Li,Kwok-Kin Wong,Kwok-Kin Wong,James J. Collins,Patrick Cahan,Trista E. North,Trista E. North,Trista E. North,Douglas A. Lauffenburger,George Q. Daley +22 more
TL;DR: This work describes a computational approach that combines gene expression analysis, previous knowledge from proteomic pathway informatics and cell signaling models to delineate key transitional states of differentiating cells at high resolution, and builds on earlier CellNet and recent trajectory-defining algorithms.
Patent
Riboregulator compositions and methods of use
TL;DR: In this paper, a variety of riboregulators, including switches, switches, and trigger and sink RNA, are used for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression.
Journal ArticleDOI
Incidence of Occupational Asthma and Exposure to Toluene Diisocyanate in the United States Toluene Diisocyanate Production Industry.
James J. Collins,Steve Anteau,Patrick R. Conner,Laura D. Cassidy,Brent Doney,Mei Lin Wang,Laura Kurth,Michael L. Carson,Don Molenaar,Carrie A. Redlich,Eileen Storey +10 more
TL;DR: Evidence that cumulative and peak exposures are associated with TDI-induced asthma is found in facilities producing toluene diisocyanate.
Journal ArticleDOI
Networking Opportunities for Bacteria
TL;DR: Recent systems biology studies in prokaryotes are highlighted, the challenges ahead are considered, and opportunities for future studies in bacterial models are suggested.