Jens Allmer

TL;DR: Analyses of the Chlamydomonas genome advance the understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.

TL;DR: Iron‐deprivation induces a transition from photoheterotrophic to primarily heterotrophic metabolism, indicating that a hierarchy for iron allocations within organelles of a single cell exists that is closely linked with the metabolic state of the cell.

TL;DR: De novo sequencing can be used to directly assign a peptide sequence to a tandem mass spectrometry spectrum and many algorithms have been proposed and a selection of them are detailed in this article.

TL;DR: An extensible framework is presented, izMiR, which allows for the unbiased comparison of existing algorithms, adding new ones, and combining multiple approaches into ensemble methods and demonstrates that combining all of the methods into one ensemble approach, for the first time, allows reliable purely computational pre-miRNA detection in large eukaryotic genomes.

TL;DR: A new high‐throughput computational strategy was established that improves genomic data mining from MS experiments, resulting in the identification of novel proteins, improved annotation of gene models, and evidence of alternative splicing.