M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
Papers
More filters
Journal ArticleDOI
Access to safety data--stockholders versus prescribers.
TL;DR: In the recent Matrixx case, the Supreme Court decided that drug-company investors require increased access to statistically nonsignificant information regarding adverse drug experiences and that Prescribers' access to the same level of information should also be increased.
Journal Article
Mousepox resulting from use of ectromelia virus-contaminated, imported mouse serum.
TL;DR: It was determined that the contaminated serum, which was purchased in late 1998, originated from China and was imported into the United States as a batch of 43 L in early 1995, and was blended into a single lot and filtered before distribution to major suppliers throughout the country.
Journal ArticleDOI
Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment
Nathaniel M. Hawkins,Pardeep S. Jhund,Andrea Pozzi,Eileen O'Meara,Scott D. Solomon,Christopher B. Granger,Salim Yusuf,Marc A. Pfeffer,Karl Swedberg,Mark C. Petrie,Sean A. Virani,John J.V. McMurray +11 more
TL;DR: The severity and variation in renal impairment, and the proportion of patients requiring NOAC cessation or dose reduction, are examined.
Journal ArticleDOI
Cardiac Myocyte Membrane Wounding in the Abruptly Pressure-Overloaded Rat Heart Under High Wall Stress
Thomas A. Fischer,Paul L. McNeil,Robert Khakee,Peter V. Finn,Ralph A. Kelly,Marc A. Pfeffer,Janice M. Pfeffer +6 more
TL;DR: It is concluded that an intense hemodynamic stress in vivo can result in histologically detectable cardiomyocyte wounding.
Journal ArticleDOI
Baseline Distribution of Participants With Depression and Impaired Quality of Life in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial
Carine E. Hamo,John F. Heitner,Marc A. Pfeffer,Hae-Young Kim,Christopher T. Kenwood,Susan F. Assmann,Scott D. Solomon,Robin Boineau,Jerome L. Fleg,John A. Spertus,Eldrin F. Lewis +10 more
TL;DR: Patients with heart failure with preserved ejection fraction, who were younger had higher New York Heart Association class or comorbid angina pectoris, had lower activity levels, lived in Eastern Europe or were taking hypoglycemic agents, were more likely to have impaired quality of life (QOL) and depression.