M
Marc A. Pfeffer
Researcher at Brigham and Women's Hospital
Publications - 815
Citations - 143710
Marc A. Pfeffer is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 166, co-authored 765 publications receiving 133043 citations. Previous affiliations of Marc A. Pfeffer include Partners HealthCare & University of Miami.
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Journal ArticleDOI
C-Reactive Protein and Risk of ESRD: Results From the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT)
Finnian R. Mc Causland,Brian Claggett,Emmanuel A. Burdmann,Kai-Uwe Eckardt,Reshma Kewalramani,Andrew S. Levey,John J.V. McMurray,Patrick S. Parfrey,Giuseppe Remuzzi,Giuseppe Remuzzi,Ajay K. Singh,Scott D. Solomon,Robert D. Toto,Marc A. Pfeffer +13 more
TL;DR: Elevated baseline CRP levels are common in type 2 diabetic patients with anemia and CKD and are associated with the future development of ESRD and the composite of death or ESRS, and similar trends were noted in competing-risk models.
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Cause of Death in Patients With Diabetic CKD Enrolled in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT).
David M. Charytan,Eldrin F. Lewis,Akshay S. Desai,Larry A. Weinrauch,Peter Ivanovich,Robert D. Toto,Brian Claggett,Jiankang Liu,L. Howard Hartley,Peter V. Finn,Ajay K. Singh,Andrew S. Levey,Marc A. Pfeffer,John J.V. McMurray,Scott D. Solomon +14 more
TL;DR: In diabetic CKD, both lower baseline GFR and higher PCR are associated with higher CV and non-CV mortality rates, particularly from sudden death and infection.
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Filtration Markers, Cardiovascular Disease, Mortality, and Kidney Outcomes in Stable Kidney Transplant Recipients: The FAVORIT Trial
Meredith C. Foster,Daniel E. Weiner,Andrew G. Bostom,Myra A. Carpenter,Lesley A. Inker,Petr Jarolim,Alin Joseph,John W. Kusek,Todd E. Pesavento,Marc A. Pfeffer,Madhumathi Rao,Scott D. Solomon,Andrew S. Levey +12 more
TL;DR: It is concluded that cystatin C and B2M are strongly associated with cardiovascular events, mortality, and kidney failure in stable kidney transplant recipients.
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Serum uric acid, influence of sacubitril-valsartan, and cardiovascular outcomes in heart failure with preserved ejection fraction : PARAGON-HF
Senthil Selvaraj,Brian Claggett,Marc A. Pfeffer,Akshay S. Desai,Finnian R. Mc Causland,Martina M. McGrath,Inder S. Anand,Dirk J. van Veldhuisen,Lars Køber,Stefan Janssens,John G.F. Cleland,Burkert Pieske,Jean L. Rouleau,Michael R. Zile,Victor Shi,Martin Lefkowitz,John J.V. McMurray,Scott D. Solomon +17 more
TL;DR: This study aimed to determine the prognostic value of serum uric acid (SUA) on outcomes in heart failure with preserved ejection fraction and whether sacubitril–valsartan reduces SUA and use of SUA‐related therapies.
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Systemic and Regional Flow Distribution in Normotensive and Spontaneously Hypertensive Young Rats Subjected to Lifetime β-Adrenergic Receptor Blockade
TL;DR: As a result of lifelong beta-adrenergic receptor blockade, CO was reduced; and this was associated with a redistribution of blood flow so that flow to the kidney, brain, and splanchnic organs could be maintained at the expense of skeletal muslce perfusion.